SNP及其在分子植物育种中的应用  

Single Nucleotide Polymorphism and its Application in Molecular Plant Breeding

作　　者：王瑞云[1] 王计平[1] 李润植[1] 

机构地区：[1]山西农业大学农学院,山西太谷030801

出　　处：《山西农业大学学报（自然科学版）》2010年第2期183-187,共5页Journal of Shanxi Agricultural University(Natural Science Edition)

基　　金：山西农业大学博士科研启动项目资助(XB2008005)

摘　　要：对于多基因控制的数量性状而言,分子标记的数量影响基因的精细定位。在全基因组内进行性状分析的关键是获得大量高通量基于标记的序列。SNP(单核苷酸多态性)是基因组中分布最广的序列变异。本文综述了QTL鉴定的必需元件和基于SNP基因分型的5个中心生化反应原理。As for the traits controlled by polygenes,sufficient number of polymorphic molecular markers play a key role in fine mapping of related traits.The availability of abundant,high-throughput sequence-based markers is the key for detailed genome-wide trait analysis.Single-nucleotide polymorphisms（SNPs） are the most common sequence variation and a significant amount of effort has been invested in re-sequencing alleles to discover SNPs.Here four elements necessary to detect QTLs are reported and five central biochemical reaction principles that underlie SNP-genotyping methods are reviewed.

关 键 词：SNP(单核苷酸多态性) 分子植物育种 QTL定位 

分 类 号：S336[农业科学—作物遗传育种]