电子废弃物拆解对女性8-羟基脱氧鸟苷水平的影响  

STUDY ON THE IMPACT OF E-WASTE DISMANTLING ON THE LEVEL OF 8-HYDROXY-2’-DEOXYGUANOSINE IN FEMALE

作　　者：杨彦[1,2] 李定龙[1] 王红梅[2] 

机构地区：[1]江苏工业学院,常州213164 [2]中国环境科学研究院

出　　处：《现代预防医学》2010年第10期1834-1836,共3页Modern Preventive Medicine

基　　金：国家科技部中国科研院所社会公益研究专项支持(HB-GY200709022)

摘　　要：[目的]研究电子废弃物拆解对人体8-羟基脱氧鸟苷(8-hydroxy-2′-deoxyguanosine,8-OH-DG)水平的影响,分析相关影响因素。[方法]对浙江台州某电子废弃物拆解地区进行卫生行为学调查,采集280名拆解区女性(暴露区209名,对照区71名)的生物样本(尿液,血液)并测定了尿中8-OH-DG的含量,采用多元回归分析血中Cu、Fe等与8-OH-DG的相关性。[结果]从事酸洗工艺的拆解者体内8-OH-DG的水平相比正常对照区人群升高,职业拆解人群的8-OH-DG水平与其血清中铜、钾、锌的含量、手工拆解和焚烧工艺呈现负相关,与血清中铁的含量、年龄、酸洗工艺呈现正相关。[结论]电子废弃物拆解中从事酸洗工艺的人群受影响较大,其尿液中8-OH-DG水平升高。[Objective] To study on the impact of e-waste dismantling on the level of 8-hydroxy-2′-deoxyguanosine and the related index in female. [Methods] We investigated the processing of e-waste recycling villages with a long-history e-waste dismantling in Taizhou of Zhejiang, a total of 280 females including occupational exposure group （ 209） and control group （71） were surveyed on their medical behaviors. The level of 8-hydroxy-2′-deoxyguanosine of urine were measured, and the relativity between 8-OH-DG concentration and heavy metals （Cu、Fe、et al.） in blood-samples were analyzed by using a multiple regression method. [Results] The level of 8-OH-DG in exposed people working on acid-bath process in E-waste recycling were found higher than that of control group, and it showed positive correlation with Fe concentration in blood samples, age and acid-bath process. At the same time, it was found negative correlated with concentration of Cu, K and Zn in serum, manual operating and incineration process. [Conclusion] E-waste dismantling activity had a great impact on the level of 8-hydroxy-2′-deoxyguanosine and the related index in female, and the level of their urine 8-OH-DG increased.

关 键 词：电子废弃物拆解 8-羟基脱氧鸟苷(8-OH-DG) 酸洗工艺 

分 类 号：R134[医药卫生—劳动卫生]