信阳农村高血压人群外周动脉病发生率及影响因素  

Prevalence of Peripheral Arterial Disease and Relative Factors in Hypertensive Patients in Xin Yang Countryside

作　　者：杨晓敏[1] 孙刚[1] 丁燕程[1] 闫旭龙[1] 闫宏[1] 吴海英[2] 周宪梁[2] 张慧敏[2] 樊晓寒[2] 惠汝太 

机构地区：[1]内蒙古科技大学包头医学院第二附属医院心内科,内蒙古高血压研究所,内蒙古包头014030 [2]中国协和医科大学阜外心血管病医院,高血压诊治中心,北京100037

出　　处：《中华高血压杂志》2010年第3期269-272,共4页Chinese Journal of Hypertension

摘　　要：目的探讨高血压患者中外周动脉病的发生率和影响因素。方法在信阳农村7个社区对年龄40～75岁人口进行横断面调查,共筛查出高血压患者4716名,调查高血压人群中外周动脉病(踝臂指数≤0.9)的发生率及相关危险因素。结果在高血压患者中,外周动脉病的发生率为8.7%。与无外周动脉病者相比,外周动脉病患者年龄更大,传统心血管病危险因素更多,包括收缩压增高[(170.1±22.6)比(166.6±22.7)mm Hg,P<0.01)]、脉压增大,血糖增高[(5.8±2.2)比(5.6±1.7)mmol/L,P<0.05],总胆固醇增高[(5.7±1.3)比(5.5±1.1)mmol/L,P<0.05],血尿酸增高。多元Logistic回归调整了年龄、性别及其他心血管病危险因素后,与外周动脉病相关的因素为:吸烟史(OR=1.65,95%CI1.18～2.29),脑卒中病史(OR=1.50,95%CI1.12～2.00),高尿酸血症(OR=1.54,95%CI1.10～2.15),总胆固醇(OR=1.12,95%CI1.02～1.23)、体质量指数(OR=0.95,95%CI0.93～0.98)。结论信阳农村高血压患者外周动脉病发生率为8.7%,外周动脉病与传统心血管病危险因素相关。Objective To investigate the prevalence of peripheral arterial disease（PAD） and its risk factors.Methods A cross-sectional study was carried out.Total 4716 patients with hypertension aged 40-75 were recruited from 7 rural communities in Xin Yang.PAD was defined as an ankle-brachial index（ABI）≤0.9 in either leg.Results The prevalence of PAD is 8.7% in patients with hypertension.Hypertensive patients with PAD were older,had more conventional cardiovascular risk factors including higher systolic blood pressure [（170.1±22.6） vs（166.6±22.7） mm Hg,P0.01] and pulse pressure,higher blood glucose [（5.8±2.2） vs（5.6±1.7）mmol/L,P0.05],total cholesterol [（5.7±1.3） vs（5.5±1.1）mmol/L,P0.05] and serum uric acid than the hypertensive patients without PAD.After adjusted for sex,age and other cardiovascular risk factors,PAD remained associated with current smoking（OR=1.65,95% CI 1.18-2.29）,history of stroke（OR=1.50,95% CI 1.12-2.00）,hyperuricemia（OR=1.54,95% CI 1.10-2.15）,total cholesterol（OR=1.12,95% CI 1.02-1.23） and body mass index（OR=0.95,95% CI 0.93-0.98） in multiple logistical regression analysis.Conclusion The prevalence of PAD is 8.7% in patients with hypertension in Xin Yang countryside.PAD is associated with conventional cardiovascular risk factors.

关 键 词：外周动脉病 高血压 发生率 影响因素 

分 类 号：R544.1[医药卫生—心血管疾病] R543[医药卫生—内科学]