紫外分光光度法测定洛索洛芬钠片的含量  

Determination of the loxoprofen sodium tablets by UV spectrophotometry

作　　者：邓滢 郭利民[2] 钟世华[3] 姚波[3] 

机构地区：[1]湖南省益阳市第三人民医院药剂科,湖南益阳413000 [2]湖南省益阳市中心医院药剂科,湖南益阳413000 [3]湖南师范大学化学化工学院,湖南长沙410081

出　　处：《中国当代医药》2010年第14期40-40,42,共2页China Modern Medicine

摘　　要：目的:建立洛索洛芬钠含量的紫外分光光度测定法。方法:采用紫外分光光度法,以水为空白对照,223nm为测定波长,测定洛索洛芬钠的含量。结果:洛索洛芬钠浓度在4.016～20.080μg/ml范围内线性关系良好(r=0.9994,n=5),平均加样回收率99.13%。结论:该法操作简便、精密度好、结果可靠,适用洛索洛芬钠片含量的快速测定。Objective： To establish ultraviolet spectrophtometry method for the determination of loxoprofen sodium. Methods： The contents of loxoprofen sodium were determined at 223 nm with water as the blank control by ultraviolet spectrophotometry. Results： The calibration curve of loxoprofen sodium was linear when its concentration range was from 4.016 to 20.080 μg/ml（r=0.999 4,n=5）, and average recovery was 99.13%. Conclusion： The method is convenient in operation, precise, reliable in results,and can be used as rapid determination for loxoprofen sodium in tablets.

关 键 词：洛索洛芬 紫外分光光度法 含量测定 

分 类 号：R927.2[医药卫生—药学]