板蓝根多糖抑制致病性大肠埃希菌细胞黏附的试验研究  

Radix Isatis Polysaccharides to Inhibit Adhesion of Pathogenic E. coli to Cell

作　　者：张红英[1] 王学兵[1] 赵现敏[1] 王亚宾[1] 陈丽颖[1] 夏平安[1] 崔保安[1] 

机构地区：[1]河南农业大学牧医工程学院,河南郑州450002

出　　处：《微生物学杂志》2010年第1期61-63,共3页Journal of Microbiology

基　　金：教育部博士点专项科研基金(20070466001);河南省基础与前沿技术研究计划项目(082300453207)

摘　　要：研究板蓝根多糖能否影响致病性大肠埃希菌对细胞的黏附。使用PK-15细胞进行了黏附试验及黏附抑制试验。在所选的4个浓度中,板蓝根多糖浓度为1.6mg/mL时,对细菌黏附细胞的抑制作用最好,黏附力由每个细胞黏附44.8个细菌降低到6.3个细菌。板蓝根多糖对致病性大肠埃希菌的细胞黏附具有抑制作用,提示该多糖具有调节肠道微生态的潜在应用价值。Effect of Radix Isatis polysaccharides （RIPS） on adhesion of pathogenic E.coli to cell was studied by adhesion test and inhibiting adhesion test on PK-15 cell.The results showed that RIPS had the best inhibition for E.coli adhesion to PK-15 cell at 1.6 mg/mL concentration among the selected four concentrations of RIPS,the number of bacteria adhesion to cells was reduced from 44.8 per cell to 6.3 per cell.Therefore,cell adhesion of E.coli can be inhibited by RIPS indicating that it may have a potential application value in regulating enteric microecology.

关 键 词：板蓝根多糖 大肠埃希菌 细菌黏附 

分 类 号：S853.7[农业科学—临床兽医学]