前列解毒胶囊联合芦氟沙星治疗慢性前列腺炎的随机双盲对照临床观察  

Qianlie Jiedu Capsule combined with Rufloxacin for chronic prostatitis:A randomized double-blind controlled clinical trial

作　　者：徐建春[1] 卢启明[1] 付立杰[1] 陈玉平[1] 

机构地区：[1]昆明医学院第一附属医院男性科,云南昆明650032

出　　处：《中华男科学杂志》2010年第2期183-186,共4页National Journal of Andrology

摘　　要：目的:中成药治疗慢性前列腺炎的双盲对照试验报导不多,本文旨在用随机双盲的方法观察前列解毒胶囊治疗慢性前列腺炎的疗效。方法:将慢性前列腺炎患者80例随机分成2组,即前列解毒胶囊+芦氟沙星组(实验组)和安慰剂+芦氟沙星组(对照组),均服药4周。采用双盲对照,所有患者治疗前及治疗4周后均以NIH-CPSI评分、行EPS常规检查。结果:两组患者经治疗4周后,NIH-CPSI总分及疼痛症状评分、排尿症状评分及生活质量评分均比治疗前有显著降低(P<0.05),EPS中WBC计数也明显减少(P<0.05)。实验组治疗后在NIH-CPSI总分、疼痛症状评分、排尿症状评分和生活质量评分方面与对照组相比也有明显改善(P<0.05),但两组治疗后在WBC计数方面无显著性差异(P>0.05)。结论:前列解毒胶囊联合芦氟沙星治疗慢性前列腺炎4周能有效缓解患者疼痛和排尿症状,改善患者生活质量,较单独应用抗生素疗效好。Objective：Few double-blind controlled trials have been reported on Chinese patent medicines for the treatment of chronic prostatitis.The purpose of this study was to investigate the therapeutic efficacy of Qianlie Jiedu Capsule for chronic prostatitis （CP） by the randomized double-blind controlled method.Methods：Eighty CP patients were equally randomized into an experimental and a control group,the former treated with Qianlie Jiedu Capsule＋Lufloxacin,and the latter given placebo＋Lufloxacin,both for 4 weeks.All the patients were evaluated by NIH-CPSI and EPS examination before and after the medication.Results：After 4-week treatment,the total score of NIH-CPSI and the scores of pain,voiding symptoms and quality of life were significantly decreased in both groups compared with the baseline（P〈0.05）,so did the leukocyte count in EPS（P〈0.05）.And the experimental group showed significant drops in the above scores as compared with the control（P〈0.05）,except in the leukocyte count in EPS（P〉0.05）. Conclusion：Qianlie Jiedu Capsule combined with Lufloxacin is highly effective for CP by relieving pain and voiding symptoms,decreasing the leukocyte count in EPS and improving the life quality of the patients.

关 键 词：慢性前列腺炎 中成药 前列解毒胶囊 芦氟沙星 

分 类 号：R697.33[医药卫生—泌尿科学]