家禽单核苷酸多态性研究与应用新进展  

Recent Progresses on Research and Application of Poultry Single Nucleotide Polymorphism

作　　者：卢立志[1,2] 李进军[2] 田勇[2] 傅衍[1] 

机构地区：[1]浙江大学动物科学学院,杭州310029 [2]浙江省农业科学院畜牧兽医研究所,杭州310021

出　　处：《农业生物技术学报》2010年第2期374-381,共8页Journal of Agricultural Biotechnology

基　　金：国家科技部国际合作项目(20071502);现代农业产业技术体系建设专项资金(NYCYTX-45-02);浙江省重大科技攻关项目(2007C12058;2009C12079)共同资助

摘　　要：单核苷酸多态性(singlenucleotide polymorphisms,SNPs)是许多生物体基因组中最普遍存在的遗传变异形式,作为新一代的分子标记具有密度高、双等位基因、易实现自动化检测等特点,已广泛应用于家禽遗传育种学的研究中。本文综述了近年来有关家禽SNP发掘、基因分型技术、多态性特征以及在遗传育种中应用的新进展,并展望了其在家禽研究中应用的前景。Single nucleotide polymorphisms（SNPs） are the most common form of genetic variation in many organisms, as a new generation of molecular markers, it has been widely used in genetics and breeding research of poultry due to the characteristics of high density, duble-allele and easy to automate detecting.In this paper, some new progresses on poultry SNP discovery, genotyping, polymorphisms characteristic and the application in genetics and breeding research were reviewed;moreover, the prospect of SNP in the research of poultry was also briefly discussed.

关 键 词：分子标记 单核苷酸多态性 家禽 应用 

分 类 号：S858.3[农业科学—临床兽医学]