复发性脑胶质瘤的手术适应征及预后  

Indications of operation for recurrent intracranial glioma and its prognosis

作　　者：王同力[1] 马晓东[1] 许百男[1] 余新光[1] 狄淬砺[1] 李方晔[1] 张义鹏[1] 

机构地区：[1]解放军总医院神经外科,北京100853

出　　处：《军医进修学院学报》2010年第6期549-550,596,共3页Academic Journal of Pla Postgraduate Medical School

摘　　要：目的探讨复发性脑胶质瘤的再手术适应征及预后。方法回顾性分析我科2005年1月-2007年12月47例再手术复发性脑胶质瘤患者的临床资料。结果47例均手术治疗,全切除27例,次全切除20例。再手术后卡氏评分(Kamofsky Performance Status,KPS)50-90,平均78.30。再手术后生存期为3月-22月,平均生存期11.62月。经多变量分析,病理类型、手术间隔、手术切除程度对改善预后有统计学意义。结论术前病理为WHOⅠ-Ⅱ级,手术间隔≥12月的复发脑胶质瘤患者,积极手术治疗可改善生活质量、延长生存时间。Objective To investigate the indications of operation for recurrent intracranial glioma and its prognosis.Methods Clinical data about 47 patients with recurrent intracranial glioma admitted to our department in January 2005-December 2007 were retrospectively analyzed.Results Of the 47 patients,27 underwent total resection and 20 subtotal of the tumor,respectively.The score for the Kamofsky performance status（KPS）after operation was 50-90（mean 78.30）.The survival time after operation was 3-22 months（mean11.62 months）.Multivariate analysis showed that pathologic type,operation interval,and surgical excision extent were related with the prognosis of patients.Conclusion Active surgical treatment can improve the quality of life of patients with their intracranial glioma relapsed≥12 months after operation and prolong their survival time if their tumor is classified as 1-2 according to the WHO classification.

关 键 词：神经胶质瘤 复发 外科手术 

分 类 号：R651[医药卫生—外科学]