急性心肌梗塞患者静脉溶栓治疗前后QT离散度变化分析  

Analyses of the change of QT dispersion in patients with acute myocardial infarction after intravenous thrombolytic therapy

作　　者：张可[1] 左明鲜[1] 章克信[1] 徐章[1] 白文伟[1] 

机构地区：[1]昆明医学院第二附属医院心内科

出　　处：《中华心律失常学杂志》1999年第1期28-29,共2页Chinese Journal of Cardiac Arrhythmias

摘　　要：目的探讨急性心肌梗塞（ＡＭＩ）患者静脉溶栓治疗前后ＱＴ间期离散度（ＱＴｄ）变化及对预后的影响。方法１５３例ＡＭＩ患者分为溶栓再通组，未通组及非溶栓组，测定其溶栓前后的ＱＴｄ，并与非溶栓组ＱＴｄ比较。结果溶栓治疗再通后ＱＴｄ明显减小，而未通组及非溶栓组ＱＴｄ增大，且后两组间ＱＴｄ比较差异无显著性（Ｐ＞０．０５）。ＱＴｄ增大者发生室性快速心律失常比率增大。结论ＡＭＩ患者ＱＴｄ明显增大，但静脉溶栓再通后，随心肌缺血改善，ＱＴｄ明显减小，同时室性快速心律失常发生率降低。Objective To investigate the change of QT dispersion(QTd) and its effect on prognosis in patients with acute myocardial infarction(AMI) after intravenous thrombolytic therapy. Methods 153 cases were divided into three groups,i.e.(1) reperfusion group of intravenous thrombolytic therapy;(2) nonreperfusion group of intravenous thrombolytic therapy;(3) nontherapy group.The QTd was measured and compared among these three groups. Results The QTd decreased in group (1),but increased in groups (2) and (3).The difference of QTd between group (2) and (3) was not significant (P>005).The incidence of complicated ventricular arrhythmias was high as the QTd increased. Conclusion The QTd in AMI increased significantly.After intravenous thrombolytic therapy,the QTd decreased as the myocardial ischemia improved and the incidence of complicated ventricular arrhythmias lowered.

关 键 词：急性 心肌梗塞 静脉溶栓 QT间期离散度 

分 类 号：R542.220.5[医药卫生—心血管疾病]