成人肺炎支原体肺炎临床新特点回顾分析  

Retrospective analysis of new clinical characteristics in adult patients of mycoplasma pneumoniae pneumonia

作　　者：冯学威[1] 李澎[1] 刘宏 赵立[1] 

机构地区：[1]中国医科大学附属盛京医院呼吸科,沈阳110004

出　　处：《中国实用内科杂志》2010年第5期452-454,共3页Chinese Journal of Practical Internal Medicine

基　　金：国家自然科学基金资助项目(30770955);辽宁省教育厅基金资助课题(05L360);辽宁省科技计划基金(2009225010-17)

摘　　要：目的分析成人支原体肺炎患者的临床特点,探讨支原体肺炎诊断和治疗的新特点。方法对2008年4月至2009年8月中国医科大学附属盛京医院呼吸科血清学证实的80例成人支原体肺炎患者的临床特点进行回顾性分析,分析内容包括患者一般情况,临床主要症状体征、影像学特点以及治疗情况。结果 80例患者多无基础疾病,超过65岁占5%,CURB-65评分0～2者占98.75%。CT影像上出现多样化改变,除磨玻璃影外,球形病灶、团块影、浸润性改变、病变游走以及纵隔淋巴结增大等常见。大环内酯类抗生素总体疗效不佳。结论成人支原体肺炎临床出现新的变化趋势,临床症状加重,影像学变化多样,治疗难度增加。Objective To explore the new clinical diagnosis and treatment characteristics of mycoplasma pneumoniae pneumonia. Methods Retrospective analysis of clinical characteristics was conducted in 80 adult patients with serologically proven mycoplasma pneumoniae pneumonia, including basic situation, main clinical symptoms and signs,radioactivity characteristics and therapy condition. Results There were 36 cases （45 % ）of male and 44 cases （55 % ） of female in the 80 patients and there was no significant difference （ P 〉 0. 05 ） in sex. Most patients had no basic diseases. 5% patients were above 65 yrs old. 98.75% patients had 0 -2 CURB-65 scores. Consistent fever and cough were the main symptoms in these patients. There were multiple changes in CT images. Except ground glass attenuation, other signs such as consolidation, global or tumor-like shadow, scattered multiple patchy infiltration shadow,pleural effusions and enlarged mediastinal lymph nodes or migrated lesions were commonly seen. Macrolides antibiotics had poor effect. Conclusion New changing tendency of adult mycoplasma pneumoniae pneumonia has occurred, clinical symptoms are severer with multiple changes in radioactivity and the treatment has become more difficult.

关 键 词：肺炎 支原体肺炎 

分 类 号：R5[医药卫生—内科学]