新生儿红斑狼疮5例分析  

Neonatal Lupus Erythematosus:Analysis of 5 Cases

作　　者：崔荣[1] 李萍[1] 李建红[1] 冯进云[1] 刘建中[1] 罗均芬[1] 申美兰[1] 

机构地区：[1]深圳市儿童医院皮肤科,广东深圳518026

出　　处：《中国皮肤性病学杂志》2010年第5期436-437,共2页The Chinese Journal of Dermatovenereology

摘　　要：目的探讨新生儿红斑狼疮(NLE)的诊断和治疗方法。方法对5例NLE患儿的临床表现及实验室检查进行分析,并复习相关文献。结果患儿皮损类似SCLE,局限或全身分布,以颜面、躯干及四肢末端为重,患儿及其母亲ANA、抗Ro/SSA及/或抗La/SSBIgG抗体均阳性,心电图检查未见心脏传导阻滞,未经治疗数周后自然消退。结论根据皮损表现和实验室检查可诊断新生儿红斑狼疮,一般不需治疗。To explore the diagnosis and treatment of patients with neonatal lupus erythematosus. Methods The clinical and experimental findings in the five cases of NLE were analysis and the related literatures were reviewed. Results All patients had lesions resembling subacute cutaneous lupus erythematosus on the face and/or in the trunk, and extremities. ANA and anti Ro/SSA IgG and/or anti La/SSB IgG antibodies were found in the sera of the five infants and their mothers. Electrocardiogram revealed no congenital heart block. The rash faded several weeks with no particularly treatment. Conclusion The diagnosis of the five cases of NLE can be confirmed by clinical and experimental features and no particularly treatment were needed in general.

关 键 词：红斑狼疮 新生儿 

分 类 号：R593.24[医药卫生—内科学]