泌尿系细菌L型感染及对抗生素耐药性的检测  

Detection of bacterial of L-forms and its antibiotic resistance in patients with urinary infection

作　　者：郑文平[1] 

机构地区：[1]韩城市人民医院外科,陕西韩城715401

出　　处：《现代泌尿外科杂志》2010年第3期219-220,234,共3页Journal of Modern Urology

摘　　要：目的探讨泌尿系细菌L型感染情况及其对常用抗生索的耐药性,为临床诊治提供实验依据。方法用改良Kagan培养基对临床疑为泌尿系感染者的尿液分离培养,并对分离获得的细菌L型进行药物敏感试验。结果泌尿系L型细菌感染率为42.17%(35/83),其中大肠埃希氏菌L型占37.14%(13/35)。分离出的细菌L型对丁胺卡那霉素、庆大霉素、诺氟沙星、环丙沙星、青霉素G等耐药性较高。结论临床对疑为泌尿系感染者应同时检测细菌及其L型,并根据药敏试验结果联合用药,以杀菌并阻止其变为L型。Objective To study bacterial L-forms and their antibiotic resistance in patients with urinary infection and to provide scientific evidences for clinical diagnosis and treatment. Methods 83 urine samples were cultivated with ordinary culture media and L-form bacteria culture media,and then drug sensitivity tests were conducted on obtained bacteria L-forms. Results The infection rate of bacterial L-forms was 42.17% （35/83） in patients with urinary infection,37.14% （13/35）of which was Escherichia coll. The obtained bacterial L-forms presented high resistance rate to amikacin,gentamicin,norfloxacin, ciprofloxacin and penicillin G. Conclusion Bacteria and their L-forms should both be detected, considered and treated in patients with urinary infection.

关 键 词：泌尿系感染 细菌L型 药物敏感试验 

分 类 号：R691.3[医药卫生—泌尿科学]