微波消解ICP-MS定量测定人体血清中14种微量元素  

Simultaneous Determination of 14 Elements in Human Serum by ICP-MS with Microwave Digestion

作　　者：英锡相[1] 包永睿[1] 李伟[2] 赵友林[3] 何学红[3] 马进[3] 张文洁[1] 

机构地区：[1]辽宁中医药大学药学院 [2]辽宁中医药大学基础医学院,沈阳市110032 [3]辽宁中医药大学附属医院,沈阳市110032

出　　处：《光谱实验室》2010年第3期1128-1131,共4页Chinese Journal of Spectroscopy Laboratory

基　　金：辽宁省自然科学基金项目资助(No.20072073)

摘　　要：采用电感耦合等离子体-质谱法测定慢性肾炎患者及健康人血清中的Na、Mg、Al、K、Ca、Cr、Mn、Fe、Ni、Cu、Zn、As、Se和Pb等14种元素,以In作为内标进行基体效应的补偿,该方法快速灵敏,回收率为91.08%—l08.0%,相对标准偏差小于5.0%,结果令人满意,可应用于临床慢性肾炎患者血清中多种微量元素的同时检测。The 14 kinds of trace element,Na,Mg,Al,K,Ca,Cr,Mn,Fe,Ni,Cu,Zn,As,Se and Pb in serum of chronic glomerulonephritis and health person were simultaneously determined by ICP-MS.In was as the internal standard to compensate the matrix effect.The recoveries are in the range of 91.08%—l08.0% with the relative standard deviations of less than 5.0%.The validated method for determining trace elements is simple,fast,which can be employed to the determination of trace elements in serum of chronic glomerulonephritis.

关 键 词：电感耦合等离子体-质谱法 慢性肾炎 血清 微量元素 

分 类 号：O657.63[理学—分析化学]