AMI患者hs-CRP水平及外周血淋巴细胞计数与心功能关系的临床研究  

Correlation of hs-CRP and Peripheral blood lymphocyte count with cardiac function in patients with acute myocardial infa

作　　者：曾元杰 

机构地区：[1]汕头市潮阳区大峰医院,515100

出　　处：《中国实用医药》2010年第15期43-44,共2页China Practical Medicine

摘　　要：目的通过对hs-CRP与外周淋巴细胞计数在急性心肌梗死(AMI)发作期间的监测,探讨与心功能的相互关系。方法随机选取健康志愿者32例(对照组)和急性心肌梗死患者106例,连续3d测定其空腹血清hs-CRP浓度及血常规,取其平均值为测定值,并用彩色多普勒分别检测出他们的左室射血分数(LVEF)。结果急性心肌梗死(AMI)组血清hs-CRP明显升高,外周血淋巴细胞计数明显降低,两组比较差异有统计学意义(P<0.05);并且血清hs-CRP水平与心功能(LVEF)呈负相关(P<0.05),外周血淋巴细胞计数水平与心功能(LVEF)正相关(P<0.05)。结论急性心肌梗死患者血清hs-CRP水平明显升高,与心功能(LVEF)呈负相关,而外周血淋巴细胞计数则正相关。Objective To examine the correlation of the High sensitive-CRP ,（hs-CRP） levels and peripheral blood lymphocyte count with Cardiac function.Methods The serum levels of hs-CRP and peripheral blood lymphocyte count were detected in 32 healthy adults and 106 patients with AMI.The datas of remodeling and cardiac function （LVEF） were measured by echocardiography in all persons.Results Compared with control group,AMI patients had high serum levels of hs-CRP（P〈0.05）.The lower LVEF class,the higher the levels of hs-CRP and the lower the peripheral blood lymphocyte count （P〈0.05）.The levels of hs-CRP were negative corelation with cardiac function （LVEF） （P〈0.05）, but peripheral blood lymphocyte count were positive（P〈0.05）.Conclusion The levels of serum hs-CRP significantly increased in the AMI patients.Th e levels of hs-CRP are negative correlation with cardiac function （LVEF）, but peripheral blood lymphocyte count were positive.

关 键 词：急性心肌梗死 高敏C反应蛋白 外周血淋巴细胞计数 心功能 

分 类 号：R542.22[医药卫生—心血管疾病]