我院122例循环系统药物不良反应分析及防范对策  

Adverse Reaction of Circulatory System Drugs: Analysis and Preventative Strategy(122 Cases)

作　　者：蔡长春[1] 李景苏[1] 

机构地区：[1]解放军白求恩国际和平医院药剂科,石家庄050082

出　　处：《临床误诊误治》2010年第5期485-486,共2页Clinical Misdiagnosis & Mistherapy

摘　　要：目的分析循环系统药物的不良反应特点,为临床合理用药提供依据。方法利用我院自行设计的药物不良反应（adverse drug reaction,ADR）监测报告系统对2007年1月~2008年12月全程监测的122例循环系统药物引起的ADR进行回顾性分析,并统计数据。结果作用于循环系统的药物发生ADR居同期我院ADR第二位,其中中成药制剂、血管紧张素转换酶抑制剂和硝酸酯类居前三位,临床表现以皮疹居首位。结论临床医生应加强中药制剂、血管紧张素转换酶抑制剂和硝酸酯类药物的合理运用,并注意观察ADR,以提高患者用药安全性。Objective To analyze the adverse reaction of circulatory system drugs and to provide reasonable guidelines for clinical purpose.Methods Drug adverse reaction,originated by circulatory system drug application in 122 cases monitored during January 2007~December 2008,were analyzed by inductive statistics according to clinical manifestation,drugs and treatment methods.Results ADR induced by circulatory system drug ranked the second in our hospital in the same period and Chinese formulated medicine,angiotensin converting enzyme inhibitor and nitrate were the top three categories.Erythra ranked the first in adverse drug reaction symptoms.Conclusion ADR observation and rational application of chinese formulated medicine,angiotensin converting enzyme inhibitor and nitrate can promote the safe use of drugs.

关 键 词：中成药 血管紧张素转换酶抑制剂 硝酸酯类 心血管药物 不良反应 

分 类 号：R972[医药卫生—药品]