发生脑短暂性缺血发作的飞行员脑α波优势频率的不确定性分析  

Dominant Frequency Uncertainty Analysis of EEG α Activity in Pilots with Transient Ischemic Attacks

作　　者：周传岱[1] 韩东旭[1] 刘月红 翟怡娟 李岩松 

机构地区：[1]航天医学与医学工程

出　　处：《航天医学与医学工程》1999年第2期84-87,共4页Space Medicine & Medical Engineering

摘　　要：目的探讨脑短暂性缺血发作（ＴＩＡ）引起的脑功能紊乱的生物电特征，为飞行员、航天员选拔提供可参考的评价方法。方法用ＣＦＭ－８ＤＥＥＧ监护仪记录了１２名飞行员（男性，３０±５）发生ＴＩＡ后的ＥＥＧ，应用脑波频率涨落分析系统分析了脑α波优势频率的不确定性，并与２０名健康飞行员进行了比较。结果发生ＴＩＡ但ＥＥＧ正常的飞行员，其主频出现优势涨落几率与健康飞行员比有明显的差异（Ｐ＜０．０１），且主频几率优势比指数Ｉ≥０，而健康飞行员主频几率优势比Ｉ＜０；与２０名健康飞行员比较，相对熵值减少明显（Ｐ＜０．０５）。发生ＴＩＡ且局部出现ＥＥＧ改变的飞行员不但Ｉ≥０且脑波出现优势频率慢化。结论应用脑α波优势频率不确定性分析评价脑的缺血反应比ＥＥＧ判读更优越。该研究结果不仅为ＴＩＡ脑功能病理生理研究提供了评价参数，而且也为飞行员和航天员选拔提供了评价方法。Objective To study the characteristics of EEG after tramsient ischemic attack and to offer reference for screening procedure of aircrew and astronaut selection. Method The dominant frequency uncertainty of alpha band EEG in 12 pilots(males; age 30±5) with transient ischemic episodes in middle cerebral artery(MCA) territories and in 20 normal healthy pilots was analyzed with frequency fluctuation analysis. Result The dominant probability of the main frequency coinciding with sites affected by transient ischaemic attack(TIA) in patient pilots was higher than that in healthy pilots (P< 0.01 ),and the dominant probability ratio logarithmic index I≥0 in all patient pilots with normal EEG, but I<0 in all healthy pilots. It was also found that not only I≥0, but the second component shifted to lower frequency(8 Hz) in patients with slight focal EEG alterations,i.e. slowing of frequency. The relative entropy values (percentage) were decreased significantly in pilots with TIA as compared with healthy pilots (P<0.05). Conclusion The dominant frequency uncertainty analysis of alpha band showed clear superiority of computerized evaluation over routine visual assessment for the diagnosis of minor cerebral ischemia. It offers not only a possibility of studying pathophysiological functional parameter, but also the reference for screening procedure in aircrew and astronaut selection.

关 键 词：脑电图 不确定性 短暂性缺血发作 飞行员选拔 

分 类 号：R338.1[医药卫生—人体生理学] R851.3[医药卫生—基础医学]