Si基底上DNA分子的自组装  

Self-Assembly of DNA Molecules on Si Substrate

作　　者：刘艳梅[1] 张宇[1] 王德军[1] 

机构地区：[1]吉林大学化学学院,长春130012

出　　处：《吉林大学学报（理学版）》2010年第3期503-507,共5页Journal of Jilin University:Science Edition

基　　金：国家自然科学基金(批准号:20673049;20703020)

摘　　要：利用自组装方法将DNA分子吸附于Si基底表面,并通过原子力显微镜(AFM)观察不同质量浓度的DNA溶液在Si基底表面进行自组装后的结构:当DNA溶液的质量浓度较低时,Si基底表面会吸附单个、拉伸、环状的分子;当DNA溶液的质量浓度为60～160ng/μL时,在Si基底表面会形成网状结构;当DNA溶液的质量浓度超过200ng/μL时,仅形成DNA薄膜.实验结果表明,可以利用该方法制作基于Si材料的DNA分子器件.DNA was attached onto Si substrate by self-assembly. The AFM images show that the structures of DNA on Si substrate depended on the concentration of DNA solution：at a low concentration of DNA,the single,stretched,cricular DNA molecules were absorbed on Si substrate; at 60~160 ng/μL DNA,the DNA network structures were formed; at a concentration of DNA higher than 200 ng/μL,DNA film could just form. These results suggest that it is possible to develop a DNA molecule device by this method.

关 键 词：DNA分子 Si基底 自组装 分子器件 原子力显微镜(AFM) 

分 类 号：O647[理学—物理化学]