参术片抗氧化作用的实验研究  

Lab Study of Anti-oxidation Effects of Shenzhu Table

作　　者：沈启良[1] 

机构地区：[1]河南中医学院第一附属医院,河南郑州450000

出　　处：《中医学报》2010年第3期481-482,共2页Acta Chinese Medicine

摘　　要：目的:探讨参术片的抗氧化作用。方法:用参术片对D-半乳糖致亚急性衰老模型小鼠进行实验,分大、小两个剂量组,设空白对照组、阳性对照组、模型对照组、参术片大、小剂量组。结果:参术片大、小剂量和六味地黄丸能显著降低D-半乳糖亚急性衰老模型小鼠血清中升高的NO水平(P<0.01),能显著升高血清中SOD、GSH-Px的水平(P<0.01),能显著降低血清中脂质代谢产物MDA的水平(P<0.01),能显著增加胸腺指数及脾脏指数(P<0.01)。结论:提示了参术片可通过抗氧化作用及对NO的影响防治多种疾病的发生,从而延缓衰老。Objective：To investigate the anti-oxidation effect of Shenzhu table. Method：sub-acute senile model mice were used. They were divided into 5 groups randomly,including control group,model group,positive group,high dose group and low dose group. Results：NO and MDA in serum were decreased by Shenzhu table and Liuweidihuang pill. Meanwhile,SOD and GSH-Px were enhanced by them. Thymus index and spleen index were also increased dramatically（ P 0. 01）. Conclusion：Anti-oxidation and the effect on NO of Shenzhu table were used to prevent and treat many illness and postphone the senile.

关 键 词：参术片 亚急性衰老模型 一氧化氮 抗氧化 

分 类 号：R285.5[医药卫生—中药学]