应用PCR技术诊断CMV孕期及先天性感染的研究  

USING PCR TECHNIQUE TO DIAGNOSE CMV INFECTION IN PREGNANCY AND IN- TRAUTERINE

作　　者：殷宪敏[1] 欧知硕[1] 宋文刚 高丽英[1] 

机构地区：[1]泰山医学院附属医院邮,政编码271000

出　　处：《新生儿科杂志》1999年第1期11-13,共3页The Journal of Neonatology

基　　金：山东省卫生厅科研基金

摘　　要：为了解本地区巨细胞病毒（ＣＭＶ）孕期及先天性感染的现状，用ＰＣＲ技术对 １５６例孕妇及其所生新生儿１１４例分别进行了ＣＭＶ－ＤＮＡ检测。结果显示孕妇ＣＭＶ－ＤＮＡ检出率为 ７．０５％，有异常妊娠史的孕妇，ＣＭＶ－ＤＮＡ的检出率明显增高。孕妇ＣＭＶ－ＤＮＡ阳性者，其新生儿检出率为４４．４％（４／９）。因此我们认为，该地区ＣＭＶ孕妇及新生儿感染仍然常见。In order to investigate the condition of CMV infection in pregnancy and in- trauterine in our area, we used PCR technique to examine urine from 156 pregnant women and cord blood from 114 newborns respectively. The result showed that the rate of CMV in- fection in pregnant women was 7.05%. It was as high as 44. 4% in the fetuses whose moth- ers were CMV-DNA-positive. The result also showed that the rate was much hhgher in the pregnant women having history of abnormal pregnancy. We came to the conclusion that the rate of CMV infection in pregnancy and intrauterine in our area is more common

关 键 词：新生儿感染 PCR 诊断 巨细胞病毒 妊娠并发症 

分 类 号：R722.130.4[医药卫生—儿科] R714.251[医药卫生—临床医学]