CT引导125I粒子治疗非小细胞肺癌的辐射防护护理干预  

Radiation protective nursing intervene of 125I seed implantation in non-small cell lung carcinoma guided by CT

作　　者：付丽[1] 张遵城[2] 于兆晨[3] 郑广钧[3] 田美荣[3] 

机构地区：[1]天津医科大学第二医院护理部,300211 [2]天津医科大学第二医院医学科 ,300211 [3]天津医科大学第二医院胸外科 ,300211

出　　处：《国际放射医学核医学杂志》2009年第5期312-315,共4页International Journal of Radiation Medicine and Nuclear Medicine

摘　　要：目的探讨在CT引导下125I粒子植入微创治疗非小细胞肺癌（NSCLC）辐射防护护理干预的措施及注意事项。方法对89例NSCLC患者实施有计划和验证的125I粒子植入治疗，进行围手术期的全程防护护理干预，观察分析植入治疗的成功率、疗效参数和并发症发生率。结果科学合理的辐射防护护理干预能保障放射性粒子植入的剂量学分布符合有效和微创的原则，植入治疗成功率达到100％，局部控制有效率为96．7％，1年生存率为92．2％；早期和晚期放射反应发生率分别为14．6％和1．1％。未出现放射性泄漏污染事件。结论包含全程放疗计划和验证的125I粒子植入疗法，结合科学的辐射防护护理干预措施，对提高NSCLC的疗效和明显降低并发症的发生具有重要的临床价值。Objective To research radiation protective nursing intervene and important notice of 125I seeds minimally invasive implantation in non-small cell lung careinoma（NSCLC） by CT. Methods Under the system of therapy planning system （TPS） and posologic validation, 125I seeds were implanted in 89 cases of NSCLC patients. The consistent radiation protective nursing intervene was used in perioperative period management. The operative successful rate, therapeutic effect and complication rate was observed. Results The scientific radiation protective nursing intervene can ensure that the radioactive dose distribution of 125I seed implantation brachytherapy is consistent with the principles of effective and minimally invasive. The operative successful rate was 100%. The local control rate and 1 year survival rate respectively was 97.4% and 92.2% .But the early and later incidence rate of radioactive damaging effect was 14.6% and 1.1% respectively. Leakage of radioactive contamination has not occurred. Conclusion The consistent TPS and posologic validation 125I seeds implantation integrated scientific radiation protective nursing intervene. It is very important to improve the therapeutic effect of NSCLC and reduce the incidence of complications.

关 键 词：碘放射性同位素 癌 非小细胞肺 近距离放射疗法 辐射防护 护理干预 

分 类 号：R473.73[医药卫生—护理学]