Brφnsted酸离子液体催化合成N-叔丁基丙烯酰胺  

Synthesis of N-tert-butylacrylamide catalyzed by Brφnsted acidic ion liquids

作　　者：赵地顺[1] 申晓冰[1] 李倩[1] 张妍[1] 杨洁[1] 

机构地区：[1]河北科技大学化学工程与制药学院,河北石家庄050018

出　　处：《化学工程》2010年第5期42-45,90,共5页Chemical Engineering(China)

基　　金：国家自然科学基金资助项目(20576026)

摘　　要：合成并表征了Brφnsted酸离子液体,用于催化Ritter反应合成N-叔丁基丙烯酰胺。通过Hammett函数法测定了离子液体的酸度函数值。通过考察各种离子液体的催化活性及重复使用性能,选定Brφnsted酸离子液体[EPy][HSO4]为催化合成N-叔丁基丙烯酰胺,研究了反应时间、反应温度等因素对酰化反应的影响,同时考察了离子液体的循环使用性能。得到其较佳工艺条件:反应温度50℃,反应时间6h,收率达到85.6%。分离后的离子液体经真空干燥后重复使用5次,催化活性基本不变。Brφnsted acidic ion liquids were synthesized and characterized. N-tert-butylacrylamide was synthesized by Ritter reaction with Brφnsted acidic ion liquids. The acidity function was determined by using Hammett function. According to the study of catalytic activity and the reusability of various ion liquids,[EPy][HSO4] was chosen to synthesize N-tert-butylacrylamide as the catalyst. The effects of the reaction conditions on the acidylation reaction results,such as reaction time,reaction temperature were examined and the optimal conditions were obtained. Under the optimal reaction conditions of 50 ℃,6 h ,the conversion can be 85.6%. The ion liquids can be repeatedly used for five times after distillation and vacuum drying without considerable loss of activity.

关 键 词：Brφnsted酸离子液体 Ritter反应 Hammett函数 N-叔丁基丙烯酰胺 

分 类 号：TQ225.261[化学工程—有机化工]