羚羊角胶囊对老年单纯收缩期高血压患者血压变异性、脉压及左心室质量的影响  

Impact of saiga horn capsule on blood pressure variability,pulse pressure and left ventricular mass in elderly patients with isolated systolic hypertension

作　　者：方晓江[1] 钱宝庆[1] 

机构地区：[1]浙江中医药大学附属广兴医院,杭州310007

出　　处：《中华中医药杂志》2010年第6期936-938,共3页China Journal of Traditional Chinese Medicine and Pharmacy

摘　　要：目的:观察羚羊角胶囊对老年单纯收缩期高血压患者血压变异性、脉压和左心室质量的影响。方法:选择78例单纯收缩期老年高血压患者,在服用苯那普利基础上服用羚羊角胶囊4个月,比较治疗前、后24h收缩压、舒张压、脉压、左心室质量的变化。结果:服羚羊角胶囊4个月后24h及日间收缩压变异性、舒张压变异性、夜间收缩压变异性、24h及日间平均压变异性明显降低(P<0.05)、脉压缩小(P<0.05)、左心室质量在加服羚羊角胶囊后明显下降(P<0.05),24h收缩压和舒张压有下降趋势但差异无显著性。结论:在常规西药治疗基础上加用羚羊角胶囊更有助于平稳、持续安全降压,缩小脉压,更好保护靶器官。Objective：To observe the efficacy of saiga horn capsule combining with benazapril on blood pressure variability,pulse pressure and left ventricular mass in elderly patients with isolated systolic hypertension （ISH）.Methods：78 elderly patients with ISH were treated with saiga horn capsule combining with benazapril for 4 months.We compared the change of 24hours systolic blood pressure （SBP）,24hours diastolic blood pressure （DBP）,pulse pressure （PP） and left ventricular mass.Results：After four months treatment,reduction of 24 hour SBP variability,day SBP variability,DBP variability,night SBP variability day,24 hour and day average BP variability,pulse pressure and left ventricular mass had statistical signifi cance （P〈0.05）.Reduction of 24 hour systolic blood pressure and diastolic blood pressure had not statistical signifi cance （P〈0.05）.Conclusion：The elderly patients with ISH treated with saiga horn capsule and benazapril can lower blood pressure,pulse pressure more effective,therefore protect target organ better than with benazapril only.

关 键 词：单纯收缩期高血压 羚羊角 血压变异性 脉压 

分 类 号：R544.1[医药卫生—心血管疾病]