清血八味颗粒质量标准的研究  

Study on quality standards of Qingxue Bawei Granule

作　　者：许莉勇[1] 

机构地区：[1]浙江医药高等专科学校,宁波315100

出　　处：《中华中医药杂志》2010年第6期942-944,共3页China Journal of Traditional Chinese Medicine and Pharmacy

摘　　要：目的:确定清血八味颗粒质量标准。方法:通过薄层鉴别方法对处方中牛黄、紫草进行定性鉴别。运用高效液相色谱法对栀子中的栀子苷进行含量测定。结果:薄层色谱斑点清晰,阴性对照无干扰。含量测定栀子苷量在0.128-0.640μg之间有良好的线性关系,相关系数r=0.9999。回收率为99.02%,RSD=1.8%(n=5)。结论:所建立的方法可靠,能准确地进行定性、定量检测,可用于该制剂的质量控制。Objective：To establish the quality standard for Qixue Bawei Granule.Methods：Calculus Bovis and Radix Arnebiae were identified by TLC.Jasminoidin was determined by a HPLC method.Results：TLC spots were clear and specific.A good linear relationship between peak area and concentration of Jasminoidin was found at the range of 0.128-0.640μg with a correlation coefficient （r=0.9999）.The average recovery of Jasminoidin was 99.02% as RSD 1.8 %（n=5）.Conclusion：The methods were reliable,accurate and specific.It may be used to the quality control of the preparation.

关 键 词：清血八味颗粒 薄层色谱 高效液相法 栀子苷 

分 类 号：R286[医药卫生—中药学]