CRP、FIB在重度烧伤早期并发SIRS变化规律的临床研究  

The clinical researches on the changing law in severe burn early stage about acute phase protein CRP and FIB

作　　者：张承飞[1] 卢学军[1] 王一兵[1] 付晋凤[1] 

机构地区：[1]南京医科大学附属淮安第一医院烧伤整形科,江苏淮安223300

出　　处：《湖南中医药大学学报》2010年第4期39-40,63,共3页Journal of Hunan University of Chinese Medicine

摘　　要：目的探讨重度烧伤患者早期血浆C反应蛋白(CRP)和纤维蛋白原(FIB)的变化规律。方法对2008年5月～2009年3月收治的按住院先后顺序随机选择36例TBSA≥30﹪烧伤病人,其中24例不符合SIRS诊断标准为对照组;12例符合SIRS诊断标准为重度烧伤SIRS组。烧伤患者分别于伤后3、7、14 d各时相点抽外周静脉血定量检查CRP和FIB。结果血清CRP值在重度烧伤SIRS组伤后3 d、7 d、14 d与对照组各时相点差异有统计学意义(P<0.01),血浆FIB值差异均无统计学意义(P>0.05)。结论重度烧伤早期同时检测CRP和FIB可作为是否并发SIRS或处于SIRS阶段早期诊断方法。Objective Focuses on on the changing law in severe burn early stage about acute phase protein CRP and FIB. Methods There were 36 cases of burned patients who came from our hospital in May, 2008 to March,2009 TBSA ≥ 30 %. 24 cases of them which have TBSA ≥30 % but not conforming to the standards of SIRS are regarded as the control group; Other 12 cases conforming to the standards of SIRS are regarded as SIRS group. The patients were taken two blood samples by definite quantity, which were detceted as CRP and FIB, at 6 am on 3dth,7dth and 2wth respectively after they had been injured. Results The mean of serum CRP and FIB have def inite difference in SIRS group and the control group（P〈0,01）. Conclusion simultaneous detecting the mean of blood may early diagnose complicating SIRS.

关 键 词：重度烧伤 C反应蛋白 纤维蛋白原 全身炎症反应综合征 

分 类 号：R644[医药卫生—外科学]