复尔康注射液血管、肌肉刺激性及溶血试验研究  

Study on Vascular and Muscle Irritant and Hemolysis of Fu-er-kang Injection

作　　者：白映涛[1] 李蓉[2] 任美萍[2] 刘明华[2] 肖顺汉[2] 李茂[2] 陈海霞[2] 

机构地区：[1]四川省德阳市中江县人民医院,618100 [2]泸州医学院药理毒理研究室

出　　处：《实用心脑肺血管病杂志》2010年第5期614-615,共2页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

基　　金：四川省科技厅支撑计划(2008G0036)

摘　　要：目的观察复尔康注射液给予动物后的血管、肌肉刺激性情况及溶血情况,对复尔康注射液的安全性进行评价。方法分别采用家兔耳缘静脉注射给药、股四头肌肌肉注射给药,取相应组织病理切片检查观察复尔康注射液血管、肌肉刺激性;家兔红细胞悬液中加入复尔康注射液,观察其溶血情况。结果复尔康注射液静脉给药、肌肉注射给药后对血管和肌肉无刺激性,对家兔红细胞体外不溶血。结论复尔康注射液静脉、肌肉注射给药无刺激性,无溶血反应。Objective Observe Fu-er-kang injection on Vascular and muscle irritant and hemolysis,and evaluate the security of Fu-er-kang injection.Methods After injecting Fu-er-kang injection into the marginal vein of the ear and quadriceps of the rabbit,pathological section method was used to study the Vascular and muscle irritant.Observe the hemolysis after adding Fu-er-kang injection in red blood cell suspension of rabbit.Results Fu-er-kang injection have no irritant after injecting Fu-er-kang injection into the vein and muscle.Fu-er-kang injection have no hemolysis on red blood cell suspension of rabbit in vitro.Conclusion Fu-er-kang injection didn′t exhibit vascular and muscle irritant and hemolysis.

关 键 词：复尔康注射液 血管刺激性 肌肉刺激性 溶血 

分 类 号：R994.11[医药卫生—毒理学]