超声检测主动脉瓣钙化与冠心病的相关性研究  

Relationship between Aortic Valve Calcification and Coronary Artery Disease

作　　者：楼建英[1] 龚东[2] 彭健[2] 张伟[1] 王达理[1] 钱维源[3] 

机构地区：[1]解放军第454医院心内科,南京市210002 [2]珠海市中山大学附属第五医院心内二科 [3]解放军第454医院特诊科,南京市210002

出　　处：《中国超声医学杂志》2010年第5期431-434,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的 探讨主动脉瓣钙化与冠心病发病之间的关系.方法 回顾性研究同期行冠状动脉造影检查和超声心动图检查患者 1 075例,分析主动脉瓣钙化与冠心病的相关性.结果 冠心病组主动脉瓣钙化的检出率明显高于非冠心病组（33.0%对14.1%,χ2＝52.44,P〈0.001）,多因素Logistic回归分析结果显示,除传统危险因素如年龄、性别、高脂血症、糖尿病外,主动脉瓣钙化与全组冠心病的发病之间亦呈显著相关,按年龄分层后分析可见,对于中青年患者,主动脉瓣钙化是冠心病有意义的独立预测因子.结论 主动脉瓣钙化与全组冠心病发病之间存在显著的相关性,对于中青年患者而言,主动脉瓣钙化具有冠心病的独立预测价值.Objective To explore the relationship between aortic valve calcification （AVC） and coronary artery disease （CAD） . Methods From June 2004 to June 2009, clinical date of 1075 consecutive inpatients underwent transthoracic echocardiography （TTE） and coronary arteriography （CAG） at the same time were analyzed retrosp ective- ly in the study. Results The incidence of AVC was significantly higher in CAD group than in normal coronary group （33.0%vs14.1%, x2= 52.44, P〈0. 001）, Multiple logistic regression analysis identified age （P〈0. 001）, gender （P〈0. 001）, diabetes mellitus （P=0. 009）, hyperlipemia （P=0. 002） and AVC （P=0. 014） as independent predictors for the positive prevalence of coronary arteriography. Conclusions There was a significant association between the presence of AVC and CAD. The presence of AVC was an independent predictor of CAD in middle and young aged patients.

关 键 词：主动脉瓣钙化 冠状动脉疾病 动脉粥样硬化 超声心动描记术 冠状动脉造影术 

分 类 号：R541.4[医药卫生—心血管疾病] R445.1[医药卫生—内科学]