尿路感染致病菌分布及尿液pH值改变在临床防治中的作用  

Role of pathogens distribution and urine pH changes in urinary tract infection for clinical prevention and treatment

作　　者：周鹏[1] 卢根生[1] 张庆华[1] 林吓聪[1] 

机构地区：[1]第三军医大学西南医院全军泌尿外科中心,重庆400038

出　　处：《第三军医大学学报》2010年第10期1099-1101,共3页Journal of Third Military Medical University

摘　　要：目的探讨尿路感染(urinary tract infection,UTI)常见致病菌的分布及其尿液pH值的特征。方法采集606例本院UTI细菌培养阳性结果及感染后尿pH值数据,分析致病菌的分布,按照菌属将主要致病菌分为3组,统计分析不同菌属感染尿pH值的差异。结果UTI致病菌总例数606例,埃希菌属186例(30.7%),感染尿液pH值集中地分布于6.21～6.33;念珠菌属152例(25.1%),尿pH值集中分布于5.81～5.95;肠球菌属86例(14.2%),感染尿pH值集中分布于6.10～6.28。比较3组尿液pH值发现念珠菌属感染的尿pH值明显偏酸(P<0.05)。结论UTI尿pH值发生改变,不同的UTI致病菌所对应的尿pH值不同且差别较大,通过调整尿pH值能更有效地抑制致病菌的生长,提高抗菌药物的药物效应。Objective To explore the distribution of pathogens and the characteristics of the urine pH values in urinary tract infection （UTI）, and provide a new idea for clinical prevention and treatment of UTI. Methods The data of 606 strains of pathogens and the infected urine pH values from urinary samples of patients with UTI from January 2007 to November 2009 in our hospital were obtained. The distribution of pathogens was detected, and these pathogens were divided into 3 groups according to the genus. Urine pH value of different pathogens was analyzed. Results Among 606 strains from UTI, the group of escherichia ranked the first with 186 strains （30.7%）, and the infected urine pH by this bacteria ranged from 6.21 to 6. 33. A total of 152 strains of candida were detected （25.1%）, and the infected urine pH value was from 5.81 to 5.95. There were 86 strains of enterococcus detected （ 14.2% ） , and the infected urine pH was from 6.10 to 6.28. By contrasting the infected urine pH of these 3 groups, the infected urine pH by candida was acidic significantly （P 〈0.05）. Conclusion The urine pH from UTI is changed. The urine pH infected by different pathogens are different. So it might be feasible to control UTI by adjusting the urine pH value to suppress the germ growth and to improve the therapeutic effect of antibacterial agents.

关 键 词：尿路感染 致病菌 尿PH值 

分 类 号：R691.3[医药卫生—泌尿科学] R446.12[医药卫生—外科学]