高效液相色谱法测定工作场所空气中丙烯酸  

Determination of acrylic acid in air of workplace by high performance liquid chromatography

作　　者：林小葵[1] 李玉萍[1] 冯婉丽[1] 范衍琼[2] 

机构地区：[1]广东省江门市新会区疾病预防控制中心,广东江门529100 [2]广东省江门市职业病防治所,广东江门529000

出　　处：《中国卫生检验杂志》2010年第5期1014-1015,共2页Chinese Journal of Health Laboratory Technology

摘　　要：目的:建立工作场所空气中丙烯酸的溶剂解吸-高效液相色谱测定方法。方法:以硅胶管采集空气中丙烯酸,用甲醇解吸后高效液相色谱测定。结果:丙烯酸浓度在10μg/ml～120μg/ml(以采集3 L空气样品计,相当于空气中丙烯酸的浓度为0.10 mg/m3～120 mg/m3)范围内线性关系良好,回归方程y=37922944.3x+1527.6,r=0.9992(n=6),检出限为0.06μg/ml;相对标准偏差在2.3%～4.7%之间;平均解吸效率94.9%;200 mg硅胶吸附45μg丙烯酸,密闭放置一周,损失率(10%。结论:本法适用于工作场所空气中丙烯酸的浓度测定。Objective：To establish a method for determination of acrylic acid in the air of workplace by high performance liquid chromatography.Methods：Silica gel tube adsorption and solvent desorption were used for sampling of acrylic acid and analysis was performed by HPLC.Results：The relative standard deviation in the range of 0.10 μg/ml～120 μg/ml was 2.3%～4.7%.Regression equation is y=37922944.3x＋1527.6,r=0.9992（n=6）.Detection limit was 0.06 μg/ml.The average desorption efficiency was 94.9%.In a tube containing 200 mg silica gel,45 μg of acrylic acid could be adsorbed.Keep this tube tightly closed for a week,the acrylic acid could still remain stable with a loss rate ﹤10%.Conclusion：The method is compatible with concentration detection of acrylic acid in the air of workplace.

关 键 词：丙烯酸 工作场所 硅胶管 溶剂解吸 高效液相色谱 

分 类 号：O657.72[理学—分析化学]