百蕊草矿质元素含量测定和主成分分析  

Determination and principal components analyze of mineral elements in different population of Thesium chinense

作　　者：罗夫来[1] 郭巧生[1] 

机构地区：[1]南京农业大学中药材研究所,江苏南京210095

出　　处：《中国中药杂志》2010年第10期1226-1230,共5页China Journal of Chinese Materia Medica

基　　金：国家科技基础条件平台项目(2005DKA21000)

摘　　要：目的:测定百蕊草矿质元素含量,分析百蕊草特征元素及评价药材质量。方法:运用ICP法分析百蕊草药材矿质元素含量,用主成分分析法对百蕊草特征元素和药材质量进行分析和评价。结果:百蕊草含有17种以上矿质元素。其中铁(Fe),锌(Zn),铜(Cu),锰(Mn),铬(Cr),钴(Co),镍(Ni),锶(Sr),硼(B)等9种为人体必需微量元素,钙(Ca),磷(P),钾(K),钠(Na),镁(Mg)等5种为人体必需宏量元素。B,Mg,Mn,Zn,Cu等5种具明显抗癌活性的元素在百蕊草中含量丰富。Mn和Zn均在100μg.g-1左右,Mg高达1 898.000～3 137.725μg.g-1。对人体有益元素Fe也较高(>500μg.g-1)。主成分分析发现,选择4个因子(F1,F2,F3,F4)即可对百蕊草药材进行综合评价。其综合评价函数为F=0.444 77F1+0.237 71F2+0.167 28F3+0.150 24F4。不同居群百蕊草药材的综合评价得分在0.189～0.627,Zn,Cu,Mg,P,K,铝(Al),Fe,Cr,Na,Co,铅(Pb),Mn,B,Ca等14种元素为百蕊草药材特征元素。结论:百蕊草含有17种以上矿质元素。其中Zn,Cu,Mg,P,K,Al,Fe,Cr,Na,Co,Pb,Mn,B,Ca等14元素为百蕊草药材特征元素。来安七里和来安施官2个居群百蕊草药材质量较好。Objective： To determine the concentration of mineral elements and analyze the principal components in Thesium chinense.Method： Mineral elements were determined by ICP-DES.Principal components analysis（PCA） was used toanalyze and evaluate the characteristic elements.Result： T.chinense contained more than 17 mineral elements,Fe,Zn,Cu,Mn,Cr,Co,Ni,Sr,B,Ca,P,K,Na,Mg,Mg,Mn,Zn and Cu were abundance in T.chinense.The concentration of Mn and Zn were about 100 μg·g-1,Mg was from 1 898.0 to 3 137.73 μg·g-1,Fe 500 μg·g-1.PCA concluded that four factors（F1,F2,F3,F4） could be used to evaluate the quality of T.chinense.The function is following： F=0.444 77F1＋0.237 71F2＋0.167 28F3＋0.150 24F4.The scores of different populations of T.chinens were from 0.627 to 0.189.Zn,Cu,Mg,P,K,Al,Fe,Cr,Na,Co,Pb,Mn,B and Ca were the characteristic elements of T.chinense.Conclusion： T.chinense contain more than 17 mineral elements.Zn,Cu,Mg,P,K,Al,Fe,Cr,Na,Co,Pb,Mn,B and Ca were the characteristic elements of T.chinense.

关 键 词：百蕊草 矿质元素 主成分分析 

分 类 号：R284.1[医药卫生—中药学]