“药物使用剂量和频次智能化监控系统”用于非抗菌药物监控的实施及效果分析  

Analysis on Application of Intelligent Monitoring System for Dosage and Frequency of Drugs in the Monitoring of Non-antimicrobials

作　　者：翟晓波[1] 何志高[1] 鲍思蔚[1] 文传民 

机构地区：[1]同济大学附属东方医院药学部,上海市200120 [2]大通医药信息技术有限公司,上海市201203

出　　处：《中国药房》2010年第21期1973-1975,共3页China Pharmacy

基　　金：上海市卫生局科研课题(2006087);同济-国药医院管理研究基金(TJGY0803);上海市科委生物医药重点项目(8411951300)

摘　　要：目的:借助"药物使用剂量和频次智能化监控系统"促进非抗菌药物合理使用。方法:基于医院信息系统,通过"药物使用剂量和频次智能化监控系统"实现非抗菌药物使用剂量和频次与患者年龄、体质量、体表面积、肾功能状况等信息相链接,并随机抽取我院1天的住院患者非抗菌药物处方(1315张)进行审查。结果:对无需按年龄、肾功能等调整剂量和频次的药物,系统审查出单次剂量过大而频次适中警示200条,单次剂量过大而频次不足警示91条,单次剂量适中而频次不足警示43条,单次剂量适中而频次过多警示41条,单次剂量过小和频次适中或不足警示15条。而对需按年龄、肾功能等调整剂量和频次的药物,系统审查出剂量过大和(或)频次过多警示11条。结论:这种链接方式切实可行,当非抗菌药物处方中出现不符合说明书规定的使用剂量和(或)频次时,能够被该系统识别,而其实用价值有待实践检验。OBJECTIVE： To promote rational use of non-antimicrobials based on Intelligent Monitoring System for Dosage and Frequency of Drugs.METHODS： Base on the information system of hospital,dosage and frequency of drugs were collected from Intelligent Monitoring System for Dosage and Frequency of Drugs and connected with patients’ ages,weights,body surface areas and renal functions.1 315 hospitalized prescriptions of non-antimicrobials were randomly collected from our hospital one day.RESULTS： There were 200 warnings of overdosage each time and moderate frequency,91 warnings of overdosage each time and inadequate frequency,43 warnings of moderate dosage each time and inadequate frequency,41 warnings of moderate dosage each time and excessive frequency,15 warnings of inadequate dosage each time and moderate or inadequate frequency for drugs that needn’t be adjusted according to age and renal functions.There were 11 warnings of overdosage and excessive frequency for drugs that should be adjusted according to patients’ age and renal function.CONCLUSION： This kind of connection is practical,when prescriptions of non-antimicrobials which violate the rules of dose and （or） frequency are identified by system.But the significance of Intelligent Monitoring System for Dosage and Frequency of Drugs should be proved by practice.

关 键 词：药物使用剂量和频次智能化监控系统 非抗菌药物 剂量 频次 肌酐清除率 体表面积 

分 类 号：R952[医药卫生—药学]