Photodegradation of fluoroquinolone antibiotic gatifloxacin in aqueous solutions  

作　　者：GE LinKe CHEN JingWen ZHANG SiYu CAI XiYun WANG Zhuang WANG ChunLing 

机构地区：[1]Key Laboratory of Industrial Ecology and Environmental Engineering (MOE), Department of Environmental Science and Technology,Dalian University of Technology, Dalian 116024, China

出　　处：《Chinese Science Bulletin》2010年第15期1495-1500,共6页

基　　金：supported by the National Basic Research Program of China (Grant No. 2006CB403302);National Natural Science Foundation of China (Grant No. 20777010);the Program for Changjiang Scholars and Innovative Research Team in University of China (Grant No.IRT0813)

摘　　要：Fluoroquinolone antibiotics (FQs) are frequently detected as emerging pollutants in aqueous environments.In this study,kinetics,influencing factors and mechanisms on the photodegradation of gatifloxacin,a representative FQ,were investigated.The photodegradation follows the pseudo-first-order kinetics.Gatifloxacin photodegrades with a quantum yield of (5.94 ± 0.95) × 10 3 in pure water and undergoes direct photolysis as well as self-sensitized photodegradation.The FQ photodegrades slower in freshwater and seawater than in pure water,which is attributed to the integrative effects of pH and the aqueous dissolved matter (e.g.,humic acids and NO 3-) on the photodegradation.A toxicity test using Vibrio fischeri revealed the formation of hazardous photoproducts.Fluoroquinolone antibiotics （FQs） are frequently detected as emerging pollutants in aqueous environments.In this study,kinetics,influencing factors and mechanisms on the photodegradation of gatifloxacin,a representative FQ,were investigated.The photodegradation follows the pseudo-first-order kinetics.Gatifloxacin photodegrades with a quantum yield of （5.94 ± 0.95） × 10 3 in pure water and undergoes direct photolysis as well as self-sensitized photodegradation.The FQ photodegrades slower in freshwater and seawater than in pure water,which is attributed to the integrative effects of pH and the aqueous dissolved matter （e.g.,humic acids and NO 3-） on the photodegradation.A toxicity test using Vibrio fischeri revealed the formation of hazardous photoproducts.

关 键 词：喹诺酮类抗生素 加替沙星 光降解 水溶液 氟 影响因素 降解机制 量子产率 

分 类 号：R96[医药卫生—药理学]