鉴定干细胞源胰岛素分泌细胞的方法及其利弊  

Methods of Identifying the Insulin Producing Cells Induced from Stem Cells and their Pros and Cons

作　　者：王跃春[1] 张洹[2] 郑乔丹[1] 黄晓恩[1] 林佳盈[1] 

机构地区：[1]暨南大学医学院生理学系,广东广州510632 [2]暨南大学医学院血液病研究所,广东广州510632

出　　处：《医学与哲学（B）》2010年第5期56-57,共2页Medicine & Philosophy(B)

基　　金：广东省自然科学基金博士科研启动项目;项目编号:9451063201002957;广东省医学科研基金资助项目;项目编号:2008350;暨南大学第六批本科生科技创新工程项目(2010)

摘　　要：在诱导各种干细胞向胰岛素分泌细胞(insulin producing cells,IPCs)分化的研究中,或多或少地存在着分化效率低、分化细胞不够成熟以及分泌产物的性质难以确定等问题,而IPCs的功能决定了其治疗糖尿病的效果,也是衡量各种诱导方案的重要指标。如何合理、科学地对IPCs进行形态与功能鉴定本文对此加以探讨。There are some problems such as low differentiation efficiency, immature of induced cells and ambiguous quality of secretory production in the research of inducing insulin producing cells （IPCs） from various stem cells. However, the functions of IPCs cannot only determine their treatment effect on diabetes but also evaluate the efficiency of the induction protocols, how to identify the function of IPCs scientifically and effectively. We will set forth this topic based on our scientific research.

关 键 词：胰岛素分泌细胞 功能 鉴定 方法 

分 类 号：R587.1[医药卫生—内分泌]