妊娠期妇女泌尿生殖道解脲脲支原体与人支原体感染调查及药敏分析  

Infection Survey and Drug Sensitivity Analysis of Ureaplasma urealyticum and Mycoplasma hominis in Urogenital Tract of Pregnancy Women

作　　者：明岩[1] 

机构地区：[1]杭州市萧山区第一人民医院产科,浙江杭州311201

出　　处：《中华医院感染学杂志》2010年第11期1625-1627,共3页Chinese Journal of Nosocomiology

摘　　要：目的观察妊娠期妇女泌尿生殖道解脲脲支原体感染,并对其耐药情况进行分析。方法入选512例妊娠期妇女,采集各受试者泌尿生殖道标本,应用法国生物梅里埃公司支原体试剂盒进行解脲脲支原体(Uu)和人支原体(Mh)感染培养和药敏检测分析。结果 512份标本支原体培养阳性率为45.1%,其中单纯Uu阳性率为31.3%,单纯Mh阳性率为6.3%,Uu和Mh混合感染阳性率为7.6%;妊娠期妇女泌尿生殖道支原体对多西环素、交沙霉素和米诺环素较为敏感;对环丙沙星、氧氟沙星和罗红霉素的耐药率较高。结论妊娠期妇女泌尿生殖道支原体感染较高,以解脲脲支原体感染为主,耐药性检测有助于指导临床治疗。OBJECTIVE To investigate the infection and drug sensitivity of mycoplasma in urogentital tract of pregnancy women. METHODS Five hundred and twelve pregnancy women were enrolled, and the specimens of urogenital tract were collected. Cultivation and drug sensitivity of Ureaplasma urealyticum（Uu） and Mycoplasma hominis（Mh） were carried out using Mycoplasma kit of French bioMerieux Company. RESULTS The positive rate of mycoplasma infection was 45. 1% in the 512 pregnancy women, the positive rate of Uu infection alone was 31.3%, the positive rate of Mh infection alone was 6.2% ,and the mixed infection rate of Uu and Mh was 7.6%. The mycoplasmas in urogenital tract of pregnancy women were sensitive to doxycycline, josamycin and minocycline hydrochloride; and resistant to ciprofloxacin, ofloxacin and roxithromycin. CONCLUSIONS The positive rate of mycoplasma infection in urogenital tract of pregnancy women is high, the main infection is UU and the drug sensitivity analysis is helpful to guide clinical treatment.

关 键 词：妊娠期妇女 泌尿生殖道 支原体 感染 药敏 

分 类 号：R375[医药卫生—病原生物学]