高尿酸血症相关因素及其与中医证型的关系研究  

Relationship of Risk Factors of Hyperuricemia with Traditional Chinese Medical Syndrome Patterns

作　　者：黄庆仪[1] 周新华[1] 吕天越[1] 吴芷兴[1] 吴小秋[1] 

机构地区：[1]广东省中医院珠海医院,广东珠海519015

出　　处：《新中医》2010年第6期27-28,共2页New Chinese Medicine

基　　金：广东省中医药局科研课题(编号:2008036)

摘　　要：目的:通过对体检人群中高尿酸血症患者相关因素的调查,探讨高尿酸血症相关因素及其与中医证型的关系。方法:以2008年度在广东省中医院珠海医院体检中心进行健康体检的珠海市干部为研究对象,按照预先制定的临床观察表格,开展相关因素调研,筛查出高尿酸血症人群,调查结束后进行统计分析。结果:实际调查和检测了3653人,筛查出高尿酸血症1294人,结果显示:高尿酸血症总患病率为35.42%,并随年龄增长而上升,男性患病率(43.74%)显著高于女性(15.39%);高尿酸血症人群合并高胆固醇血症、高甘油三酯血症、高低密度脂蛋白胆固醇血症、低高密度脂蛋白胆固醇血症、高血糖的发生率显著高于非高尿酸血症人群(P<0.05)。高尿酸血症组高血压病的患病率比非高尿酸血症组略高,但差异无显著性意义(P>0.05)。脾虚夹痰湿证型为高尿酸血症患者的临床主要证型。结论:脾虚夹痰湿证型为高尿酸血症患者的临床主要证型,其发病与性别、年龄、血脂、血糖水平有密切相关性。Objective:To explore the relationship of risk factors of hyperuricemia (HUA) with traditional Chinese medical syndrome patterns. Methods: Cadres in Zhuhai city who had physical examination in Zhuhai Hospital Affiliated to Guangdong Provincial Hospital of TCM in 2008 were enrolled into the study. Risk factors of HUA were investigated with clinical trial questionnaire, and the crowd with hyperuricemia was identified and was used for the further study. Results: Totally, 3653 subjects were enrolled into the study, and of them, 1294 were confirmed as HUA, with the morbidity rate being 35.42%. The morbidity rate was increased with the age, and 43.74% in the male, higher than that in the female(15.39%). HUA patients complicated with higher serum levels of cholesterol, triglyceride, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol had a higher incidence of hyperglycemia that those patients without HUA (P<0.05). The incidence of hypertension in HUA patients was higher than that in patients without HUA , but the difference was insignificant (P>0.05). The dominated syndrome pattern was spleen deficiency complicated phlegm-damp in HUA patients. Conclusion: Spleen deficiency complicated phlegm-damp is the dominated syndrome pattern in HUA patients. The morbidity rate of HUA is closely related with the gender, age, blood lipid level and blood glucose level.

关 键 词：高尿酸血症 中医证型 血糖 血脂 血压 性别 

分 类 号：R589.7[医药卫生—内分泌]