Solvent-and Catalyst-free Synthesis and Antifungal Activities of α-Aminophosphonate Containing Cyclopropane Moiety  

作　　者：PAN Li LIU Xing-hai SHI Yan-xia WANG Bao-lei WANG Su-hua LI Bao-ju LI Zheng-ming 

机构地区：[1]State Key Laboratory of Elemento-Organic Chemistry, National Pestieidal Engineering Centre（Tianjin） Tianjin Key Laboratory of Pesticide Science, Nankai University, Tianjin 300071, P. R. China [2]Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, P. R. China

出　　处：《Chemical Research in Chinese Universities》2010年第3期389-393,共5页高等学校化学研究（英文版）

基　　金：Supported by the National Basic Research Program of China(No.2010B12606)

摘　　要：Nine new a-aminophosphonate derivatives containing cyclopropane moiety have been synthesized via conventional and microwave irradiation methods under solvent- and catalyst-free condition. The structures of the title compounds have been confirmed by ^1H NMR, ^31p NMR FTIR, EI-MS and FTICR-MS. Their antifungal activities were evaluated in vivo and some of the compounds were found to exhibit excellent antifungal activities against Corynespora cassiicola, Pseudomonas syringae pv. Lachrymans, Pseudoperonospora cubensis and Sclerotinia sclerotiorum.Nine new a-aminophosphonate derivatives containing cyclopropane moiety have been synthesized via conventional and microwave irradiation methods under solvent- and catalyst-free condition. The structures of the title compounds have been confirmed by ^1H NMR, ^31p NMR FTIR, EI-MS and FTICR-MS. Their antifungal activities were evaluated in vivo and some of the compounds were found to exhibit excellent antifungal activities against Corynespora cassiicola, Pseudomonas syringae pv. Lachrymans, Pseudoperonospora cubensis and Sclerotinia sclerotiorum.

关 键 词：Α-AMINOPHOSPHONATE IMINE Antifungal activity 

分 类 号：O627.51[理学—有机化学] TQ463.53[理学—化学]