门控运动负荷/静息心肌灌注显像在冠心病诊断中的临床价值  

The Clinical Value of Gated-exercise Load/Resting Myocardial Nuclide Imaging in Coronary Heart Disease

作　　者：王相成[1] 王雪梅[1] 王城[1] 

机构地区：[1]内蒙古医学院附属医院核医学科,呼和浩特010050

出　　处：《中国医药导刊》2010年第4期540-542,共3页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨门控心肌灌注断层显像在冠心病诊断中的诊断价值。方法:对50例疑诊冠心病患者进行运动/静息99mTc-MIBI门控心肌灌注断层显像和冠状动脉造影检查,冠状动脉狭窄>50%为冠心病的诊断标准,并将结果进行对比分析。结果:检查冠心病的灵敏度为83.84%,特异性为84.71%,准确性为91.00%。检测左前降支(LAD)病变的灵敏度为80.62%,左旋支(LCX)为75.70%,右冠状动脉(RCA)为82.87%。检测LAD病变的准确性为76.00%,LCX为79.05%,RCA为80.30%,11例冠状动脉造影显示50%～70%狭窄与门控心肌灌注断层显像的相关性较差(r=0.13,P>0.05),39例冠状动脉造影显示>70%狭窄与门控心肌灌注断层显像有良好的相关性(r=.05,P<0.05)。结论:门控心肌灌注断层显像诊断冠心病,敏感性与特异性较高,对冠心病的无创性诊断具有重要价值。Objective：To investigate the diagnostic value of Gated-exercise load/resting myocardial nuclide imaging in coronary heart disease.Methods：The study were performed on 50 patients received Gated-exercise load/resting myocardial nuclide imaging and coronary angiography.Coronary artery stenosis exceeding 50% was considered as the diagnostic criteria of CAD.The results of two group were compared.Results：Sensitivity, specificity, and accuracy in,detecting coronary artery disease（CAD） is 83.84%,84.71% and 91.00% respectively by Gated-exercise load/resting myocardial nuclide imaging; Sensitivity of, detecing left anterior descending（LAD）, left circumflex coronary artery（LCX） and right coronary artery（RCA） is 80.62%,75.70% and 82.87% respectively;accuracy of detecting LAD,LCX and RCA） is 76.00%,79,05% and 80.30% respectively.There is poor correlation between Gated-exercise load/resting myocardial nuclide imaging and coronary angiography in 11 cases which showed stegnosis degree less than 70%（r=0.13,P〉0.05）,and good correlation in 39 case more than 70%（r=0.05,P〈0.05）.Conclusion：myocardial nuclide imaging arc of great value in the diagnosis of coronary heart disease.

关 键 词：冠心瘸 门控心肌灌注断层显像 冠状动脉造影 

分 类 号：R541.4[医药卫生—心血管疾病]