骨增痹症胶囊联合弥可保治疗腰椎管狭窄症疗效观察  

Clinical Observation of The Therapeutic Effect of Guzengbizheng Capsule with Mecobalamin on Lumbar Stenosis

作　　者：高振臣 郑超华[1] 孙瑞龙[1] 陶连辉 李季英[1] 韩凤梅[1] 姚国贤[2] 

机构地区：[1]唐山市丰润区人民医院骨科,唐山064000 [2]唐山市第二医院药剂科,唐山063000

出　　处：《中国医药导刊》2010年第4期611-612,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:观察我院自制骨增痹症胶囊联合弥可保治疗腰椎管狭窄症治疗效果和安全性。方法:对我院自2007年12月～2009年12月治疗的168例腰椎管狭窄症随机分为两组:骨增痹症胶囊+弥可保组85例,口服骨增痹症胶囊1.35g/次,每天三次,弥可保0.5mg/次,每天三次;骨增痹症胶囊组83例,口服骨增痹症胶囊1.35g/次,每天三次,两组疗程均为一个月,对所有病例随访3～9个月。结果:骨增痹症胶囊+弥可保组总有效率82.3%,骨增痹症胶囊组总有效率72%,两组疗效比较无统计学意义(P>0,05)。结论:两种方案对腰椎管狭窄症均有效,骨增痹症胶囊与弥可保有协同作用且安全可靠。Objective：To observe the therapeutic effect and safety of Guzenghizheng capsule with Mecobalamin on lumbar stenosis Methods：168 patients with lumbar stenosis were randomly divided into two groups who were enrolled from Dec.2007 to Dec.2009 in our hospital.The 85 patients received Guzengbizheng capule 1.35g each time,3 times a day combined with Mecobalamin 0.Smg each time ,3 times a day.The other 83 patients received Guzengbizheng capsule 1.35g each time,3 times a day ,with a treatment course of 1 month for both groups. Follow-up time was （3-9） months.Result：The effective rates of Guzengbizheng capsule＋Mecobalamin group and Guzengbizheng group were respectively 82.3% and 72%,there was no significant difference between the two groups（P〉0.05）.The occurrence of side effect was respectively 30.6% and 26.5%,with no severe side effect.Conclusion：Guzengbizheng capsule has efficacy and high security in treating lumbar stenosis,and them is synergistic action in Guzenghizheng capsule and Mecobalamin.

关 键 词：腰椎管狭窄症 骨增痹症胶囊 弥可保(甲钴胺) 

分 类 号：R681.5[医药卫生—骨科学]