类风湿关节炎植物药治疗的研究进展  

Progress on the Traditional Chinese Medicines in Rheumatoid Arthritis Research

作　　者：郭静[1] 郭春林[1] 王永福[1] 

机构地区：[1]包头医学院第一附属医院,内蒙古包头014010

出　　处：《现代生物医学进展》2010年第9期1763-1765,共3页Progress in Modern Biomedicine

摘　　要：类风湿关节炎是一种以关节损害为主的最常见的自身免疫病。其有较高的致残及致畸率,严重危害人类健康,且DMARDs成为类风湿关节炎治疗的主流。而我国有丰富的植物药资源,近年来对于其在类风湿关节炎的治疗作用机制也成为研究的热点。主要的植物药有白芍总苷、雷公藤、青藤碱及羟基喜树碱。本文从体外研究、动物实验方面对其治疗机制进行分析与总结。Rheumatoid arthritis（RA） is the most common inflammatory joint disease and the one of the most common autoimmune diseases.The disease have higher rates of disability and deformity,affecting the health of people.At present,diaesse-modifying antirheumatic drugs become the main drug on the treatment aspects.But,China have abunding the traditional medicines and recently,the traditional Chinese medicines become the hot spot in the treament of RA.In this paper,we summarize the total glucosides of paeony,Tripterygium wilforddi,sinomenine,10-hydrocamptothecin on the role of RA in vitro and animal experiment.

关 键 词：类风湿关节炎 植物药 作用机制 研究 

分 类 号：R285[医药卫生—中药学] R593.21[医药卫生—中医学]