一例藏酋猴创伤所致多器官功能衰竭的病理学观察  

Case Report on Pathological Observation of Multiple System Organ Failure Caused by Wound in Macaca thibetana

作　　者：钟振东[1] 许跃忠[1] 钟浩[1] 易勇[1] 廖世平[1] 陈晓虎[1] 曾涛[1] 王红星[1] 

机构地区：[1]四川省医学科学院·四川省人民医院实验动物研究所,成都610212

出　　处：《实验动物与比较医学》2010年第2期132-135,共4页Laboratory Animal and Comparative Medicine

摘　　要：目的为探明藏酋猴创伤所致多器官功能衰竭的致病机理。方法对一例实验藏酋猴因创伤所致多器官功能衰竭的病例进行了系统的病理学观察。结果藏酋猴的剖检病变主要表现为肝脏肿大，肺萎缩，头部皮下组织大面积出血、坏死，腋下淋巴结、肠系膜淋巴结水肿。病理组织学表现为全身各组织器官不同程度的水肿、变性、坏死，尤以心、肺、肝、肾、肠和脑的病变较为明显。结论颅外组织损伤易导致多器官功能衰竭。Objective To explore the pathogenic mechanism of multiple system organ failure （MSOF） caused by extracranial tissue injury. Methods A Macaca thibetanas dead by extracranial tissue injury was pathologically examed. Results Gross pathology shows that there is swelling in the liver; atrophy of lung; hemorrhage and necrosis in subcutaneous tissue of head; edema in oxter lymph node and mesenterium lymph node. Histopathological examination shows that there is edema, degeneration and necrosis in many organs. The pathological changes of heart, lung, liver, kidney, intestine and brain is very distinct. Conclusion Extracranial tissue injury can cause many organ failure in Macaca speciose thibetanasare.

关 键 词：藏酋猴 多器官功能衰竭 病理学 

分 类 号：R459.7[医药卫生—急诊医学] R-332[医药卫生—治疗学]