运动后踝臂指数对下肢动脉疾病的诊断价值  

The Clinical Diagnostic Value for Post-exercise Ankle-brachial Index in Lower Extremity Arterial Disease

作　　者：罗惠玲[1] 何兆初[1] 曾昭华[1] 何文凯[1] 区碧如[1] 曾佩[1] 

机构地区：[1]广州医学院第一附属医院心内科,广东广州510120

出　　处：《广州医学院学报》2009年第6期12-14,共3页Academic Journal of Guangzhou Medical College

基　　金：广东省自然科学基金(0400870)

摘　　要：目的:探讨运动后踝臂指数(postexercise ankle-brachial index,postexercise ABI)对下肢动脉疾病(lower extremity arterial disease,LEAD)的诊断阈值和诊断价值。方法:收集本院心内科119例患者进行下肢动脉CTA检测、静息ABI和运动后ABI检测,根据影像学结果,将双下肢任一血管管腔直径狭窄≥50%为LEAD组,管腔直径狭窄<50%为非LEAD组。根据下肢动脉狭窄率与静息ABI和运动后ABI的关系绘制受试者工作特征曲线(receiver operator characteristic curve,ROC curve),比较两者的曲线下面积和诊断阈值。结果:运功后ABI曲线下面积大于静息ABI的曲线下面积(0.988比0.948,P<0.01),且敏感性和特异性均高于静息ABI。结论:运动后ABI在LEAD的筛检过程中比静息ABI更具诊断意义。Objective：To explore the test threshold and diagnostic value of postexereise ankle-brachial index （postexercise ABI） for lower extremity arterial disease （LEAD）. Methods： 119 patients registered to Department of Cardiology in our hospital were enrolled. All the patients underwent CT angiography of lower limbs,resting and post- exercise ABI measurement. According to the results of CTA,patients with 〉150% lumen stenosis of any blood vessel in any one of lower limbs were allocated to the LEAD group,arid those with 〈50% lumen stenosis were allocated to the non-LEAD group. Based on the relation between pereentage stenosis and resting/post-exercise ABI,a receiver operator characteristic curve （ROC curve） was generated in order to compare the area under curve and test threshold. Results： The area under curve for postexercise ABI was larger than that for resting ABI （0. 988 vs 0. 948, P 〈 0.01 ）, also with higher sensitivity and specificity. Conclusion： Postexercise ABI was much more efficient than resting ABI in diagnosis of LEAD.

关 键 词：下肢动脉疾病 运动后踝臂指数 ROC曲线 

分 类 号：R543.5[医药卫生—心血管疾病]