联合氟哌噻吨美利曲辛治疗餐后不适综合征的疗效观察  

Efficacy of Routine Medicine Combined with Flupentixol and Melitracen in the Treatment of Postprandial Dyspepsia Syndrome

作　　者：郭勤[1] 沈守荣[1] 唐五良[1] 王芬[1] 袁秀洪[1] 

机构地区：[1]中南大学湘雅三医院消化内科,湖南长沙410013

出　　处：《医学临床研究》2010年第5期845-847,共3页Journal of Clinical Research

摘　　要：[目的]探讨联合抗抑郁药氟哌噻吨美利曲辛（黛力新）治疗餐后不适综合征的临床疗效.[方法]将84例病程〉6个月的餐后不适综合征患者,随机分为2组,对照组42例应用内科常规治疗,治疗组42例在对照组基础上加用黛力新联合治疗,治疗时间均为12周.以餐后不适综合征症状评定量表（PDSR）评定疗效,SDS抑郁自评量表诊断抑郁症.[结果]治疗12周,治疗组及对照组显效率分别为71.7%（29/42）及47.8%（20/42）,治疗组SDS评分减少,差异有显著性（P〈0.05）.[结论]联合抗抑郁药黛力新治疗餐后不适综合征疗效显著,是一个理想的餐后不适综合征治疗方案.[Objective] To explore the clinical efficacy of routine medicine combined with flupentixol and melitracen（Deanxit） in the treatment of postprandial dyspepsia syndrome （PDS） . [Methods] A total of 84 PDS patients with the course of over 6 months were randomly divided into two groups. The treatment group （ n =42） received routine medicine plus antidepressant Deanxit. The control group （n =42） was given only routine medicine. They were all treated for 12 weeks. The clinical efficacy was assessed by PDS rating scale （PDSR）. SDS self-rating depression scale was used for diagnosing depression. [Results]After treatment for 12 weeks, the excellent rate in treatment group and control group was 71.7% （29/42） and 47.8% （20/42）, respectively. SDS score was reduced in treatment group and there was significant difference between two groups（ P 〈0.05）. [Conclusion] The routine medicine combined with antidepressant Deanxit has obvious efficacy for the treatment of PDS, so it is an ideal therapeutic schedule.

关 键 词：综合征/药物疗法 氟哌噻吨/投药和剂量 抗焦虑药/投药和剂量 

分 类 号：R971.41[医药卫生—药品]