获得性免疫缺陷综合征相关性肿瘤治疗进展  

Advances in the treatment for AIDS-associated malignancies

作　　者：张仁芳[1] 卢洪洲[1,2,3] 

机构地区：[1]复旦大学附属公共卫生临床中心感染科,上海201508 [2]复旦大学附属华山医院感染科,上海200040 [3]复旦大学上海医学院内科学系,上海200032

出　　处：《世界临床药物》2010年第6期334-338,共5页World Clinical Drug

基　　金：国家十一五重大科技攻关项目(2008ZX10001-008)

摘　　要：获得性免疫缺陷综合征(AIDS)相关性肿瘤包括卡波济肉瘤、非霍奇金淋巴瘤、原发性中枢神经系统淋巴瘤和宫颈癌,本文综述近年相关临床治疗进展。高效抗逆转录病毒治疗(HAART)的应用显著降低了AIDS相关性肿瘤的发病率。随着近几年肿瘤发病机制和治疗方法研究的深入,AIDS患者的治疗方案不断完善,其相关性肿瘤预后明显改善。This review summarizes the progress on the treatment of Kaposi sarcoma,non-Hodgkin＇s lymphomas,primary central nervous system lymphoma and cervical cancer,which are classified as acquired immune deficiency syndrome（AIDS）-associated malignancies.The introduction of highly active antiretroviral therapy（HAART） has led to marked declines in the incidence of AIDS-associated malignancies.With the recent progress in novel knowledge of pathogenesis and managements,the therapeutic regimens for AIDS have been improved continuously,thus the prognosis of AIDS-associated malignancies have been improved significantly.

关 键 词：获得性免疫缺陷综合征 AIDS相关性肿瘤 高效抗逆转录病毒治疗 

分 类 号：R512.91[医药卫生—内科学] R73[医药卫生—临床医学]