可必特雾化吸入治疗对慢性阻塞性肺疾病急性加重期患者肺功能的影响  

Effect of combivent inhalation on the lung function of patients with acute exacerbation of chronic obstructive pulmonary disease

作　　者：魏萍[1] 

机构地区：[1]北京市石景山医院呼吸内科,北京100043

出　　处：《海南医学院学报》2010年第5期572-574,共3页Journal of Hainan Medical University

基　　金：海南医学院科研基金资助学报项目(0020100152)~~

摘　　要：目的:观察可必特(复方异丙托溴铵溶液)对于慢性阻塞性肺疾病(COPD)急性加重期患者肺功能的影响。方法:将COPD急性加重期患者65例随机分为两组,治疗组35例,对照组30例,对照组给予甲基强的松龙、茶碱、抗炎、吸氧等常规治疗;治疗组在常规治疗的基础上给予可必特2.5 mL雾化吸入,每天2次,治疗5 d后两组之间肺功能进行比较。结果:两组患者治疗5 d后,(1)临床疗效比较:治疗组有效率为94.29%,对照组为76.67%,两组比较差异有统计学意义(P<0.05)。(2)肺功能指标比较:治疗组治疗后较对照组及治疗前比较差异有显著性意义(P<0.05)。结论:可必特雾化吸入对缓解COPD急性加重期是一种安全、快捷的方法,能够快速、有效的改善患者的肺功能。Objective： To study the clinical effect of combivent inhalation on the lung function of patients with acute exacerbation of chronic obstructive pulmonary disease（COPD）.Methods： 65 COPD cases with acute exacerbation were randomly divided into two groups,treatment group with 35 cases and a control group with 30.The patients in treatment group was treated with 2.5mL combivent inhalation solution twice a day combined with routine treatment including oxygen inhalation,Solu-Medrol,theophylline,anti-inflammation.And those in control group were treated with routine treatmen only.Compared the lung function indexes including forced expiratory volume（FEV）1 and FEV1/ forced vital capacity（FVC）%.Results： There were significant differences in FEV1 and FEV1/ FVC% between two groups（P〈0.05）.Conclusion： Combivent inhalation can alleviate COPD with acute exacerbation.It is a safe and fast way to quickly and effectively improve lung function.

关 键 词：慢性阻塞性肺疾病 可必特 雾化吸入 肺功能 

分 类 号：R563.9[医药卫生—呼吸系统]