非诺贝特治疗非酒精性脂肪肝疗效分析  被引量:4

Analysis of Effect of Fenofibrate in Treatment of Non-alcoholic Fatty Liver

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作  者:庄见齐[1] 黄可青[2] 郑晓辉[2] 

机构地区:[1]汕头大学医学院第一附属医院感染科,广东汕头515041 [2]汕头大学医学院第一附属医院药剂科,广东汕头515041

出  处:《中国误诊学杂志》2010年第16期3796-3797,共2页Chinese Journal of Misdiagnostics

基  金:广东省科技厅立项项目(项目编号:2009B030801319)

摘  要:目的观察非诺贝特治疗非酒精性脂肪肝(NAFL)的临床疗效及安全性。方法确诊非酒精性脂肪肝142例患者随机分成两组。治疗组76例,给予非诺贝特治疗;对照组给予易善复治疗,比较两组疗效。结果治疗组治愈率为55.3%,总有效率为75.0%,对照组分别为31.8%和45.5%,两组比较有统计学意义(P<0.01)。结论非诺贝特治疗脂肪肝疗效明显优于易善复,值得临床选择使用,无明显不良反应。Objective To observe the clinical effect and the safety of fenofibrate in treatment of non-alcoholic fatty liver.Methods 142 patients with non-alcoholic fatty liver were divided into two groups.76 cases in therapy group received fenofibrate and the others in control group received essentiale forte N.The effect was compared between the two groups.Results The cure rate was 55.3% and the total effective rate was 75.0% in therapy group,and was 31.8% and 45.5% respectively hhin control group.There was a statistical significance between the two groups(P0.01).Conclusions Fenofibrate is better in treatment of non-alcoholic fatty liver than essentiale forte N,and hasn't the adverse reaction.

关 键 词:脂肪肝/药物疗法 普鲁脂芬/治疗应用 降血脂药/治疗应用 

分 类 号:R453.9[医药卫生—治疗学] R575.5[医药卫生—临床医学]

 

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