复方贯众感冒滴鼻液的提取工艺研究  

Study on the Extraction Technique of Fufang Guanzhong Ganmao Nasal Drops

作　　者：陈德成[1] 陈芳[1] 孙红[1] 

机构地区：[1]广东省珠海市妇幼保健院,广东珠海519001

出　　处：《世界中西医结合杂志》2010年第5期406-407,432,共3页World Journal of Integrated Traditional and Western Medicine

摘　　要：目的优选复方贯众感冒滴鼻液提取工艺的最佳条件。方法以靛玉红含量为考察指标,运用L9(34)正交试验设计,考察加水量、提取时间、提取次数等因素对提取工艺的影响。结果提取时间和提取次数对检测指标均有显著影响,加水倍数为不显著因数。实验结果表明,以加水量为药材的10倍量,煎煮时间1.5 h,提取2次为该制剂的最佳提取工艺。结论正交实验的最终确定方法简便、实用、经济,符合工业化生产的要求。Objective To optimize the conditions of the extraction technique of fufang guanzhong ganmao nasal drops.Methods The content of indirubin was taken as the observation index,L9（3^4）orthogonal test was used to observe the impacts of several factors,such as water amount,extraction time and frequency,on the extraction technique.Results The extraction time and frequency impacted the determination index significantly.The water adding was not the significant factor.The experiment results indicated that the optimized extraction technique of this preparation was achieved by adding water 10 times as much as the herbal material in amount,decoction for 1.5 h and extraction twice.Conclusion The method determined finally by orthogonal test is sample,practical and economic and meets the requirement of industrial production.

关 键 词：感冒滴鼻液 靛玉红 正交试验 提取工艺 

分 类 号：R282.71[医药卫生—中药学]