非创伤性脾腹腔镜与开腹切除术临床对比研究的Meta分析  

Laparoscopic Versus Open Splenectomy in Non-Traumatic Spleen:Meta-Analysis of Clinical Cases

作　　者：万正东[1] 蔡立智[2] 胡从兵[2] 李清林[2] 邓黎[2] 

机构地区：[1]长江大学临床医学院,湖北荆州434000 [2]长江大学附属第一医院荆州市第一人民医院外科,湖北荆州434000

出　　处：《长江大学学报（自科版）（下旬）》2010年第1期J0024-J0027,共4页Journal of Yangtze University

摘　　要：目的:用Meta分析方法对国内外已发表的高质量的有关非创伤性脾腹腔镜与传统开腹切除术的临床对比研究进行综合定量分析,为非创伤性脾脏手术处理模式的选择提供参考依据。方法:收集已公开发表的比较腹腔镜脾切除术(laparoscopic splenectomy,LS)与开腹脾切除术(open splenectomy,OS)的临床对照研究,对符合条件的所有研究结果进行Meta分析(所选疾病为:地中海贫血、特发性血小板减少性紫癜、自身免疫性脾疾病及肝硬化脾亢)。结果:符合纳入标准的共6篇文献,总样本量493例。本组资料表明LS组的住院天数明显短于OS组,LS组手术并发症也少于OS组;而LS的手术时间要比OS组长,两者有显著性差异。结论:非创伤性脾腹腔镜脾切除术具有住院时间短和术后并发症发生率低等优点。更确切的结论尚须在以后的研究中纳入更多大样本的前瞻性临床随机对照性研究。Objective:The purpose of this study was to analyze the published results of laparoscopic splenectomy(LS) compared to open splenectomy (OS)to give some evidences for the choice of how to deal with splenic surgery. Methods:Evaluate strictly all the studies that have been searched and analyze the studies in high quality by means of meta-analysis. Results: Six studies were included in 493 patients. The period of hospital stay time was significantly reduced with LS versus OS (P <0.05),postoperative complications were significantly declined with LS versus OS (P <0.01),while Operative time was significantly longer in the LS group(P <0.05). Conclusions: The results of this meta-analysis suggest that LS reduces postoperative complications and hospital stay. However,the right conclusion remains to further high-quality randomized trials through the two techniques.

关 键 词：腹腔镜脾切除术 开腹脾切除术 META分析 

分 类 号：R657.6[医药卫生—外科学]