响应面法优化三羟甲基丙烷二烯丙基醚合成工艺  

Optimization of Synthetical Technology for Trimethylolpropane Diallyl Ether by Response Surface Method

作　　者：张君涛[1] 孙超[1] 赵美霞[1] 高军[1] 

机构地区：[1]山东科技大学化学与环境工程学院,山东青岛266510

出　　处：《山东科技大学学报（自然科学版）》2010年第2期86-90,共5页Journal of Shandong University of Science and Technology(Natural Science)

摘　　要：以三羟甲基丙烷、氢氧化钠和3-氯丙烯为原料,在相转移催化剂作用下,经Williamson醚化反应合成三羟甲基丙烷二烯丙基醚。研究了NaOH水溶液的质量分数、催化剂与三羟甲基丙烷的质量之比、反应温度和催化剂种类对反应收率的影响;采用三因素三水平的响应面分析法对工艺条件进行优化,得到了三羟甲基丙烷二烯丙基醚合成的最优工艺条件。结果表明:选用四丁基溴化铵作催化剂,反应温度为75.2℃,NaOH水溶液的质量分数为38.5%,催化剂的质量分数为三羟甲基丙烷的质量的14.5%时,可获得三羟甲基丙烷二烯丙基醚的最高收率91.2%。The trimethylolpropane diallyl ether was synthesized by Williamson etherification reaction taking trimethy-lolpropane,sodium hydroxide and allyl chloride as raw materials.The effects of reaction temperature,the mass fraction of NaOH,amount of catalyst and different types of catalysts on the reaction yield were researched.The reaction conditions were optimized by using the response surface method（RSM） with three factors and three levels,and then,the optimal technological condition of trimethylolpropane diallyl ether was obtained.The results show that the highest yield of trimethylolpropane diallyl ether can reach 91.2% when the reaction temperature is 75.2 ℃,the mass fraction of NaOH is 38.5% and the mass fraction of the catalyst is 14.5% of that of trimethylolpropane diallyl ether if the tetrabutylammonium bromide is selected as a catalyst.

关 键 词：三羟甲基丙烷二烯丙基醚 相转移催化 响应面法 

分 类 号：TQ264[化学工程—有机化工]