慢性肾脏病患者心血管疾病危险因素探讨  

A Survey on cardiovascular risk factors in patients with chronic kidney disease

作　　者：张晓光[1] 汪年松[1] 高许萍[1] 薛勤[1] 简桂花[1] 严艳[1] 盛晓华[1] 

机构地区：[1]上海交通大学附属第六人民医院肾脏风湿科,200233

出　　处：《临床肾脏病杂志》2010年第5期220-222,共3页Journal Of Clinical Nephrology

摘　　要：目的探讨慢性肾脏病（CKD）患者心血管疾病的危险因素。方法收集我院542例住院CKD患者的病史、实验室检查和辅助检查结果，将患者根据有无心血管疾病分为2组，根据Logistic回归分析结果探讨心血管疾病的危险因素。结果高龄、高血压、高尿酸血症、贫血、蛋白尿是CKD患者心血管疾病的危险因素；CKD1～5期患者心血管疾病的危险因素各不相同。结论CKD进展和CKD患者心血管疾病的发生拥有部分相同的危险因素；在CKD早期以传统危险因素为主，随着肾功能的恶化，非传统危险因素起主导的作用。Objective To investigate the risk factors of cardiovascular disease in chronic kidney disease（CKD） patients. Methods In a retrospective study, 542 patients with CKD were analyzed, patients were divided into cardiovascular disease （CVD） group and non-CVD group. Logistic regression was used to analyze cardiovascular risk factors in patients with CKD. Results The logistic regression analysis showed that cardiovascular risk factors in CKD patients were old age, hypertention, hyperuricemia, anemia, proteinuria. The risk factors of cardiovascular disease in CKD stage 1-5 was difference. Conclusions There are many common risk factors of progression of CKD and cardiovascular disease in CKD patients. Traditional risk factors are considered dominant in the early stages of CKD, but nontraditional risk factors become increasingly important with renal function worsens.

关 键 词：肾衰竭 慢性 心血管疾病 危险因素 

分 类 号：R181.13[医药卫生—流行病学]