哮喘发病与血栓前状态关系的研究  

Studying on the relationship between Incidence of asthma and prothrombotic state

作　　者：李风森[1] 马红霞[1] 杨剑[1] 

机构地区：[1]新疆医科大学附属中医院呼吸科,新疆乌鲁木齐830000

出　　处：《临床肺科杂志》2010年第7期913-914,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的探索血栓前状态与哮喘发病之间的关系。方法哮喘患者84例和对照组非哮喘病人63例同时检测外周血TXB2、TPA、PAI及凝血象。结果哮喘组的TXB2、TPA、PAI、凝血功能改变为非哮喘组的2.95倍,提示与哮喘发病之间有联系。哮喘组与对照组之间各血液流变学指标比较,除TPA外,余指标均有统计学差异(P<0.05)。结论哮喘发病过程中存在血栓前状态的病理改变。Objective To explore the relationship of the former state of thrombosis and the the incidence of asthma through this study.Methods 84 cases with asthma and 63 cases with non-asthma of the control group were selected to detect peripheral blood TXB2,TPA,PAI,and coagulation.Results The change of TXB2,TPA,PAI,and coagulation of the asthma group was 2.95 times that of the control group.TPA,PAI and coagulation but not TPA,changed significantly in asthma group compared with that of the control group（P〈0.05）.Conclusion The pathological changes exist in the process of asthma pathogenesis before prothrombotic state.

关 键 词：哮喘 血栓前状态 

分 类 号：R562.25[医药卫生—呼吸系统]