不同油脂日粮中添加RRR-α-生育酚琥珀酸酯对肉鸡生产性能、抗氧化和免疫功能的影响  

Effects of RRR-α-tocopherol Succinate on Performance,Antioxidant and Immune Function of Broilers Fed Different Oil Diets

作　　者：王改琴[1] 张旭晖[1] 王恬[1] 

机构地区：[1]南京农业大学动物科技学院,南京210095

出　　处：《动物营养学报》2010年第3期653-661,共9页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金："十一五"国家科技支撑计划(No.2006BAD14B03-7)

摘　　要：本试验旨在研究不同油脂日粮中添加RRR-α-生育酚琥珀酸酯(α-TOS)对肉鸡生产性能、抗氧化和免疫功能的影响。选用600只1日龄AA肉鸡,随机分为10个处理,每个处理6个重复,每个重复10只鸡。试验采用2×5因子设计,即2种油脂(新鲜油脂和氧化油脂)和5种α-生育酚类型,分别为30mg/kg all-rac-α-生育酚醋酸酯(TOA1)、30mg/kg RRR-α-生育酚醋酸酯(TOA2)及15、30、60mg/kg α-TOS(TOS1、TOS2和TOS3)。试验期为42d。结果表明:1)α-TOS和氧化油脂显著影响1～21日龄肉鸡的料重比,对其他生产性能无显著影响(P>0.05);2)随着α-TOS添加量的增加,不同油脂日粮肉鸡血清中三碘甲状腺原氨酸(T3)和促甲状腺激素(TSH)水平均升高,皮质醇显著降低,血清的抗氧化能力不同程度提高(P<0.05或P<0.01),丙二醛(MDA)含量显著降低和新城疫抗体效价升高(P<0.05);3)氧化油脂日粮使肉鸡血清激素水平、抗氧化酶活性和新城疫抗体效价均下降,低于同水平添加α-TOS新鲜油脂组(P>0.05)。结果提示,氧化油脂日粮能诱导肉鸡产生免疫应激,并导致生产性能和抗氧化功能下降;日粮中添加α-TOS能一定程度上提高肉鸡生产性能、血清抗氧化功能及机体免疫功能,且在不同油脂日粮中均以60mg/kg α-TOS添加组的作用效果最佳。To study the effects of RRR-α-tocopherol succinate on performance,antioxidant and immune function of broilers fed different oil diets,six hundred AA broilers were randomly divided into 10 treatments with 6 replicates and 10 broilers in each replicate. The experiment using a 2×5 factorial design： the oil types （fresh and oxidized oil） × α-tocopherol treatments （30 mg/kg all-rac-α-tocopherol acetate （TOA1）,30 mg/kg RRR-α-tocopherol acetate （TOA2）,15,30,and 60 mg/kg RRR-α-tocopherol succinate （TOS1,TOS2,TOS3）,respectively）. The experiment lasted for 42 days. The results showed that： 1） α-TOS and oxidized oil had no significant effect on the growth performance （P〉0.05） except the feed gain ratio of 1～21 day-old broilers; 2） by the amount of α-TOS increasing,the T3 and TSH levels in serum were increased and cortisol was significantly reduced,antioxidant capacity of serum was increased to some extent （P〈0.05 or P〈0.01）,malonaldehyde （MDA） levels were significantly reduced and the Newcastle disease antibody titer were improved （P〈0.05）; 3） compared with fresh oil diet groups,adding with the same level α-TOS,oxidized oil made serum hormone levels,antioxidant enzyme activity and Newcastle disease antibody titers decreased,but the differences were not significant （P〉0.05）. These results indicated that oxidized oil diet can provoke immune stress,leading the growth performance of broilers reduced,the antioxidant decreased. α-TOS supplementation in diet can improve the broiler growth performance in a certain extent,antioxidant indices and immune function of serum,and the best group is the 60 mg/kg dietary D-α-TOS supplementation in different oil diets.

关 键 词：RRR-α-生育酚琥珀酸酯 肉鸡 生产性能 抗氧化 免疫 

分 类 号：S831[农业科学—畜牧学] S816.71[农业科学—畜牧兽医]